The role of surfactant in the miniemulsion polymerization of biodegradable polyurethane nanoparticles

Zanetti-Ramos, Betina Giehl; Lemos‐Senna, Elenara; Cramail, Henri; Cloutet, Éric; Borsali, Rédouane; Soldi, Valdir

doi:10.1016/j.msec.2007.04.041

Cited by 29 publications

(22 citation statements)

References 20 publications

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“…In another study, it was observed that the particle diameter decreased from 292 nm to 261 nm when the amount of Tween 80 surfactant increased from 5 to 20 wt.% vs monomer (see Table 10.1) [29], in agreement with the literature data (13,50,(52)(53)(54)(55)(56)(57).…”

Section: Effect Of Surfactant Concentration On Particle Size and Latesupporting

confidence: 82%

“…However, a monomodal size distribution was also observed when the formulations were prepared with different surfactant types in concentrations above or below the CMC value [29].…”

Section: Effect Of Surfactant Concentration On Particle Size and Latementioning

confidence: 94%

“…Recently, we synthesized biocompatible nanoparticles using a natural triol (castor oil) as a monomer and isophorone diisocyanate (IPDI) in aqueous medium using the miniemulsion polymerization technique [28,29]. The stabilization of the nanoparticles was achieved by adding nonionic surfactants (Tween 80 or Pluronic F68) and olive oil as a co-stabilizer.…”

Section: Miniemulsion Polymerization Of Biodegradable Latexesmentioning

confidence: 99%

“…Also, it can be observed that even with different surfactant types, it is possible to obtain particles with similar sizes. A comparison between sodium dodecyl sulfate (SDS), polyethylene oxide) 77 -poly(propylene oxide) 29 -poly(ethylene oxide) 77 (Pluronic F68) and poly(ethyleneoxide) 20 -sorbitane monooleate (Tween 80) used in biodegradable polyurethane latex synthesized by miniemulsion polymerization was carried out by Zanetti-Ramos et al (2008) [29]. In this study the authors verified that SDS is not efficient in this system, resulting in a bimodal size distribution, with the latex comprising 463 nm and 2475 nm particles .…”

Section: Effect Of Surfactant Type On the Particle Size And Latex Yieldmentioning

confidence: 99%

“…[29]. Tween 80 is used in several hundred pharmaceutical and cosmetic products, owing to its attractive cost and low toxicity [48], as compared to SDS [49].…”

Section: Effect Of Surfactant Concentration On Particle Size and Latementioning

confidence: 99%

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Surfactant Effect in Miniemulsion Polymerization for Biodegradable Latexes

Soldi¹,

Zanetti-Ramos²,

Minatti³

2010

Miniemulsion Polymerization Technology

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Section: Effect Of Surfactant Concentration On Particle Size and Latesupporting

confidence: 82%

“…However, a monomodal size distribution was also observed when the formulations were prepared with different surfactant types in concentrations above or below the CMC value [29].…”

Section: Effect Of Surfactant Concentration On Particle Size and Latementioning

confidence: 94%

Section: Miniemulsion Polymerization Of Biodegradable Latexesmentioning

confidence: 99%

Section: Effect Of Surfactant Type On the Particle Size And Latex Yieldmentioning

confidence: 99%

“…[29]. Tween 80 is used in several hundred pharmaceutical and cosmetic products, owing to its attractive cost and low toxicity [48], as compared to SDS [49].…”

Section: Effect Of Surfactant Concentration On Particle Size and Latementioning

confidence: 99%

See 3 more Smart Citations

Surfactant Effect in Miniemulsion Polymerization for Biodegradable Latexes

Soldi¹,

Zanetti-Ramos²,

Minatti³

2010

Miniemulsion Polymerization Technology

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The effect of change of ionomer/polyol molar ratio on dispersion stability and crystalline structure of films produced from hydrophilic polyurethanes

Senevirathna

Amarasinghe

Karunaratne

et al. 2016

J of Applied Polymer Sci

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In this study, we report the effect of the DMPA/PTHF molar ratio on dispersion properties of the MDI-based hydrophilic polyurethane dispersions. In addition, the effect of the DMPA/PTHF molar ratio on the crystallinity and thermal properties of the polyurethane films prepared from dispersions are also discussed. The variation in stability was studied using a particle size analyzer. DSC and XRD analyses were used to study variations in crystallinity of films with the change of DMPA/PTHF molar ratio. FT-IR spectra were used to monitor the formation of hydrogen bonds through urethane linkages to produce hard-segment crystalline areas. The zeta potential increased with the increase of DMPA/PTHF molar ratio (hard-segment content), while particle size of polyurethane particles decreased. Hence, the stability of dispersions was increased with DMPA/PTHF molar ratio due to the increase of hydrophilicity in polymer chain. Crystallinity of the films was increased with DMPA/PTHF molar ratio due to the increase of interchain interactions through Coulombic interactions and hydrogen bonding. Consequently, crystalline melting temperature was increased with the increase of DMPA/PTHF molar ratio. However, molten films formed crystalline soft segments instead of crystalline hard segments during slow cooling.

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Degradable polyurethane nanoparticles containing vegetable oils

Valério

Rocha

Araújo

et al. 2013

Euro J Lipid Sci & Tech

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The development of colloidal delivery systems from degradable polyurethanes (PU) has attracted increasing interest as the highly variable synthetic chemistry of PU may be exploited to generate polymers having properties ranging from very soft elastomers to very rigid plastics. In this work, the synthesis of PU nanoparticles using isophorone diisocyanate, castor oil, and poly(e-caprolactone) as monomers and containing high amounts of vegetable oils as açaí oil and crodamol GTCCwas studied. The effect of surfactants Tween 80 and sodium dodecyl sulfate (SDS) and of poly(ethylene glycol) molar masses 400, 600, and 1000 g/mol on the stability, size, and nanoparticle morphology was evaluated. Stable dispersions with sizes between 50-70 nm and 170-250 nm were achieved when, respectively, SDS and Tween 80 were used as surfactant. The polyol type used in the step polymerization in miniemulsion had a major effect on the molar mass of the resulting PU nanoparticles. The effect of poly(ethylene glycol) molar masses was more pronounced when Castor oil and Tween 80 were employed. Increasing the molar mass of PEG increased the average particle size and the molar mass of the PU. Finally, a strong reduction of the molar mass of the PU nanoparticles was observed in degradation assays when those were maintained during 30 days at 37°C and pH 7.0.Practical applications: Using natural renewable oil as polyol to obtain polyurethane nanoparticles combined with incorporation of other vegetable oil therein showed good results in terms of molar mass and nanoparticle size. The simple and straightforward procedure to prepare polyurethane nanoparticles containing vegetable oils by step polymerization in miniemulsion contributes to improve the application range of these polymers.

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The role of surfactant in the miniemulsion polymerization of biodegradable polyurethane nanoparticles

Cited by 29 publications

References 20 publications

Surfactant Effect in Miniemulsion Polymerization for Biodegradable Latexes

Surfactant Effect in Miniemulsion Polymerization for Biodegradable Latexes

The effect of change of ionomer/polyol molar ratio on dispersion stability and crystalline structure of films produced from hydrophilic polyurethanes

Degradable polyurethane nanoparticles containing vegetable oils

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