Abstract:Background
Injectable poly‐l‐lactic acid (PLLA) carries the risk of nodule or microlump formation. Various methods including sonication have been tried to minimize these adverse effects of PLLA.
Aims
This study investigated the change in size, distribution, and properties of PLLA particles after sonication, and the duration of sonication needed to reach the ideal particle size.
Methods and Materials
Two indicators, the average size of PLLA particles and diameter at 90%, were measured at each timepoint: at 0, 1… Show more
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