Abstract:The 5-year survival rates for ovarian cancer are 93%, 75%, and 30% for localized, regional, and distant tumors, respectively. These vast differences in survival rates underscore the need to identify novel therapeutic targets that are effective at different stages of tumor progression to better treat all patients diagnosed with this deadly disease. Manganese superoxide dismutase (SOD2) is a mitochondrial antioxidant enzyme responsible for eliminating superoxide and preventing oxidative damage to the mitochondr… Show more
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