The role of small extracellular vesicles and microRNA as their cargo in the spinal cord injury pathophysiology and therapy
Kristyna Sintakova,
Nataliya Romanyuk
Abstract:Spinal cord injury (SCI) is a devastating condition with a complex pathology that affects a significant portion of the population and causes long-term consequences. After primary injury, an inflammatory cascade of secondary injury occurs, followed by neuronal cell death and glial scar formation. Together with the limited regenerative capacity of the central nervous system, these are the main reasons for the poor prognosis after SCI. Despite recent advances, there is still no effective treatment. Promising ther… Show more
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