The role of sICAM-1 detection in the diagnosis of acute rejection following liver transplantation

Yu, Yahong; Chen, Zhong; Ye, Qifa

doi:10.1007/s11596-006-0526-3

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…Researchers in the United Kingdom and the United States of America have analyzed the effect of mining subsidence on transportation facilities by field monitoring and laboratory testing [6,7]. Researchers in China have attempted to analyze highway stability under the influence of mining, synergy action principle of subgrade and pavement of highway by applying mechanical theories and put forward the judging method of highway damage affected by mining [8,9]. However, above achievements failed to have been widely applied.…”

Section: Present Situation Of Research On Coal Mining Subsidence Unde...mentioning

confidence: 99%

Present Situation of Research on Coal Mining Subsidence under Highway in China

Deng

Zhang

2013

AMR

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Research on coal mining subsidence under highway can be divided into two fields: research on the problems caused by coal mining under highway and research on the problems caused by highway construction above mined-out area of coal mine.The issues about safety，design and engineering are the key points restricting the safety and the construction of highway in coal mining areas. The paper completely summarized and analysed the present situation of research on coal mining subsidence under highway and the special characteristics comparing with the general building and the railway. In order to ensure the safety of existing highways and highways in planning in coal mining areas, according to the deficiency of current research, this paper put forward the future research directions of coal mining subsidence under highway.

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Section: Present Situation Of Research On Coal Mining Subsidence Unde...mentioning

confidence: 99%

Present Situation of Research on Coal Mining Subsidence under Highway in China

Deng

Zhang

2013

AMR

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Non invasive diagnosis of acute cellular rejection after liver transplantation – Current opinion

Kumar

Mohapatra

Borle

et al. 2018

Transplant Immunology

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HCN1 Channels Contribute to the Effects of Amnesia and Hypnosis but not Immobility of Volatile Anesthetics

Zhou

Liang

Liu³

et al. 2015

Anesthesia &Amp; Analgesia

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Background HCN1 channels have been identified as targets of ketamine to produce hypnosis. Volatile anesthetics also inhibit HCN1 channels. However, the effects of HCN1 channels on volatile anesthetics in vivo is still elusive. This study uses global and conditional HCN1 knockout mice to evaluate how HCN1 channels affect the actions of volatile anesthetics. Methods Minimum alveolar concentrations (MAC) of isoflurane and sevoflurane that induced immobility (MAC of immobility) and/or hypnosis (MAC of hypnosis) were determined in wild-type (WT) mice, global HCN1 channel knockout mice (HCN1−/−), floxed HCN1 channel gene (HCN1f/f) mice and forebrain-selective HCN1 channel knockout (HCN1f/f: cre) mice. Immobility of mice was defined as no purposeful reactions to tail-clamping stimulus and hypnosis was defined as loss of righting reflex (LORR). The amnestic effects of isoflurane and sevoflurane were evaluated by fear-potentiated startle in these four strains of mice. Results All MAC values were expressed as mean ± SEM. For MAC of immobility of isoflurane, no significant difference was found among wild-type, HCN1−/−, HCN1f/f and HCN1f/f: cre mice (all ~1.24-1.29% isoflurane). For both HCN1−/− and HCN1f/f: cre mice, the MAC of hypnosis for isoflurane (each ~1.05% isoflurane) were significantly increased over their nonknockout controls: HCN1−/− vs. wild-type (0.86±0.03%, P<0.001) and HCN1f/f: cre vs. HCN1f/f mice (0.84±0.03%, P<0.001); no significant difference was found between HCN1−/− and HCN1f/f: cre mice. For MAC of immobility of sevoflurane, no significant difference was found among wild-type, HCN1−/−, HCN1f/f and HCN1f/f: cre mice (all ~2.6-2.7% sevoflurane). For both HCN1−/− and HCN1f/f: cre mice, the MAC of hypnosis for sevoflurane (each ~1.90% sevoflurane) was significantly increased over their nonknockout controls: HCN1−/− vs. wild-type (1.58±0.05%, P<0.001) and HCN1f/f: cre vs. HCN1f/f mice (1.56±0.05%, P<0.001). No significant difference was found between HCN1−/− and HCN1f/f: cre mice. By fear-potentiated startle experiments, amnestic effects of isoflurane and sevoflurane were significantly attenuated in HCN1−/− and HCN1f/f: cre mice (both P<0.002 vs. wild-type or HCN1f/f mice). No significant difference was found between HCN1−/− and HCN1f/f: cre mice. Conclusions Forebrain HCN1 channels contribute to hypnotic and amnestic effects of volatile anesthetics, but HCN1 channels are not involved in the immobilizing actions of volatile anesthetics.

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The role of sICAM-1 detection in the diagnosis of acute rejection following liver transplantation

Cited by 3 publications

References 6 publications

Present Situation of Research on Coal Mining Subsidence under Highway in China

Present Situation of Research on Coal Mining Subsidence under Highway in China

Non invasive diagnosis of acute cellular rejection after liver transplantation – Current opinion

HCN1 Channels Contribute to the Effects of Amnesia and Hypnosis but not Immobility of Volatile Anesthetics

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