The role of secondary structures in the functioning of 3′ untranslated regions of mRNA
Mariya Zhukova,
Paul Schedl,
Yulii V. Shidlovskii
Abstract:Abstract3′ untranslated regions (3′ UTRs) of mRNAs have many functions, including mRNA processing and transport, translational regulation, and mRNA degradation and stability. These different functions require cis‐elements in 3′ UTRs that can be either sequence motifs or RNA structures. Here we review the role of secondary structures in the functioning of 3′ UTRs and discuss some of the trans‐acting factors that interact with these secondary structures in eukaryotic organisms. We propose potential participation… Show more
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