The role of residual renal function on potassium intake and excretion in patients on peritoneal dialysis

Claudino, Gabriele; Ramos, Christiane Ishikawa; Andrade, Laila Santos de; Pereira, Natalia Barros Ferreira; Teixeira, Renata Rodrigues; Muniz, Gisselma Aliny Santos; Leal, Maria Carolina Bezerra Di Medeiros; Cuppari, Lílian

doi:10.1007/s11255-023-03462-y

Cited by 1 publication

(1 citation statement)

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“…Their findings suggest that Kir5.1, like Kir4.1, is also an important component of the potassium sensing mechanism in the distal convoluted tubules, and that Kir5.1 is essential for regulating renal potassium excretion and maintaining potassium homeostasis. Claudino et al ( 28 ) concluded that chronic kidney disease allows for small potassium intakes. The presence of residual renal function is an important factor affecting potassium excretion, and a low-restriction diet can be adopted.…”

Section: Discussionmentioning

confidence: 99%

The potassium puzzle: exploring the intriguing connection to albuminuria

Yuan,

Wang,

Yue

2024

Front. Nutr.

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BackgroundStudies have revealed a relationship between dietary potassium intake and albuminuria, despite the fact that the human body needs a lot of potassium. Our study concentrated on the link between dietary potassium intake and albuminuria.MethodsThis study used subgroup analysis and weighted multivariate regression analysis. Data from the National Health and Nutrition Examination Survey (NHANES) were examined to determine the urinary albumin-to-creatinine ratio (ACR) and participant age (20 years or older). ACR >30 mg/g was the threshold for albuminuria.Results7,564 individuals in all were included in the study. The link between the two was significant in both our original model (OR = 0.99; 95% CI, 0.98–0.99, p < 0.0001) and the minimum adjusted model (OR = 0.99; 95% CI, 0.98–0.99, p < 0.0001). A fully adjusted model did not change the significance of the negative correlation between potassium consumption and albuminuria (OR = 0.99; 95% CI, 0.98–1.00, p = 0.0005), indicating that each unit increase in potassium intake was related with a 1% decrease in the chance of developing albuminuria. The negative correlation between potassium intake and albuminuria was not significantly influenced by sex, age, BMI, hypertension, diabetes, or smoking, according to interaction tests (p for interaction >0.05).ConclusionReduced risk of albuminuria was linked to higher dietary potassium intake. The particular mechanism linking the two still has to be explained by several inventive and prospective studies.

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Section: Discussionmentioning

confidence: 99%