The Role of Radiation Diagnostic Techniques in the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension

Мершина, Е. А.; Sinitsyn, V.

doi:10.21518/2307-1109-2016-1-16-25

Cited by 3 publications

(1 citation statement)

References 20 publications

(33 reference statements)

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“…Согласно результатам исследования Nakazawa, чувствительность ДЭКТ в визуализации дефектов перфузии составляет 96%, специфичность -76%. При этом возможность одновременной оценки сосудистого русла легких и перфузии легочной ткани с помощью ДЭКТ обладает большей точностью в диагностике ХТЭЛГ, чем сцинтиграфия легких, а также не требует специализированных ингаляционных систем [36,37].…”

Section: двухэнергетическая компьютерная томография (дэкт)unclassified

COVID-19 as a cause of chronic pulmonary hypertension: pathophysiological rationale and potential of instrumental investigations

Кобелев

Берген

Таркова

et al. 2021

Cardiovasc Ther Prev

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Coronavirus disease 2019 (COVID-19) is a poorly understood and dangerous medical problem. COVID-19-related pulmonary vessels involvement is a complex set of interrelated pathophysiological processes associated with vascular endothelial dysfunction and accompanied by thrombosis of various localization, vasomotor disorders, severe respiratory failure, as well as pulmonary embolism (PE) resulting in chronic thromboembolic pulmonary hypertension (CTEPH). According to computed tomographic pulmonary angiography, the incidence of PE in patients with COVID-19 ranges from 23 to 30%. The aim of this work was to focus the doctors' attention on the risk of pulmonary hypertension in patients after COVID-19.Despite the ability of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) to infect various organs and systems, the main and most serious complications are pulmonary infiltration, acute respiratory distress syndrome, acute respiratory failure and PE, which in some cases becomes the triggering mechanism for CTEPH development. The literature review presents data on main pathological abnormalities developing in target organs during COVID-19 and playing an important role in increasing the CTEPH risk. The paper describes the main methods of instrumental investigations of CTEPH and an algorithm for its use in COVID-19 survivors.The revealed data demonstrated that the absence of obvious signs of pulmonary hypertension/CTEPH, the cardiopulmonary system abnormalities cannot be ruled out. Therefore, it seems appropriate to actively follow up COVID-19 survivors. A thoroughly, purposefully collected anamnesis, pulmonary function tests and stress echocardiography in an ambiguous clinical situation will play a leading role as they identify cardiopulmonary disorders and provide the doctor with basic information for further planning of patient management.

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Section: двухэнергетическая компьютерная томография (дэкт)unclassified

COVID-19 as a cause of chronic pulmonary hypertension: pathophysiological rationale and potential of instrumental investigations

Кобелев

Берген

Таркова

et al. 2021

Cardiovasc Ther Prev

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Contribution of analysis of perfusion iodine map’s to diagnostic of acute pulmonary thromboembolism

Oganesyan

Sinitsyn

Мершина

et al. 2022

Medicinskaâ vizualizaciâ

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Purpose: to study the contribution of perfusion iodine maps to diagnosis of acute pulmonary embolism (PE) and compare pulmonary perfusion defects with the main imaging biomarkers of PE.Materials and methods. 130 patients with suspected acute pulmonary thromboembolism were studied using pulmonary computed tomographic angiography with perfusion iodine map`s analysis. Pulmonary embolism was revealed in 42 cases. There were evaluated: the number and level of vessel occlusion (Qanadli index), number and grades of lung perfusion defects on perfusion iodine maps (perfusion index), signs of right heart failure, changes of lung parenchyma.Results. Analysis of the data showed a strong correlation between the index Qanadli and perfusion index, rather than signs of right failure. In 3 cases, the segmental and subsegmential pulmonary embolism was revealed form the iodine map’s analysis only.Conclusion. Thus, perfusion iodine maps improve the diagnosis of acute pulmonary embolism due to characterizing the changes of pulmonary microcirculation. From our data, the iodine maps can be employed as a prognostic tool for further therapy.

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Eurasian Association of Cardiology (Eac) Guidelines for the Diagnosis and Treatment of Chronic Thromboembolic Pulmonary Hypertension (2020)

Чазова¹,

Мартынюк

Валиева³

et al. 2021

Evrazijskij kardiologičeskij žurnal

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Disclaimer The EAC Guidelines represent the views of the EAC, and were produced after careful consideration of the scientific and medical knowledge, and the evidence available at the time of their publication. The EAC is not responsible in the event of any contradiction, discrepancy, and/or ambiguity between the EAC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to good use of healthcare or therapeutic strategies. Health professionals are encouraged to take the EAC Guidelines fully into account when exercising their clinical judgment, as well as in the determination and the implementation of preventive, diagnostic, or therapeutic medical strategies; however, the EAC Guidelines do not override, in any way whatsoever, the individual responsibility of health professionals to make appropriate and accurate decisions in consideration of each patient’s health condition and in consultation with that patient and, where appropriate and/or necessary, the patient’s caregiver. Nor do the EAC Guidelines exempt health professionals from taking into full and careful consideration the relevant official updated recommendations or guidelines issued by the competent public health authorities, in order to manage each patient’s case in light of the scientifically accepted data pursuant to their respective ethical and professional obligations. It is also the health professional’s responsibility to verify the applicable rules and regulations relating to drugs and medical devices at the time of prescription.

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The Role of Radiation Diagnostic Techniques in the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension

Cited by 3 publications

References 20 publications

COVID-19 as a cause of chronic pulmonary hypertension: pathophysiological rationale and potential of instrumental investigations

COVID-19 as a cause of chronic pulmonary hypertension: pathophysiological rationale and potential of instrumental investigations

Contribution of analysis of perfusion iodine map’s to diagnostic of acute pulmonary thromboembolism

Eurasian Association of Cardiology (Eac) Guidelines for the Diagnosis and Treatment of Chronic Thromboembolic Pulmonary Hypertension (2020)

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