The role of quantitative D-dimer levels in the follow-up and differential diagnosis of pulmonary thromboembolism and community-acquired pneumonia

Varol, Ayhan; Köktürk, Nurdan; Kılıç, Hatice; Aydoğdu, Müge; Ekim, Numan

doi:10.3906/sag-1011-9

Cited by 5 publications

(2 citation statements)

References 24 publications

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“…For their part, Varol et al found that if D-dimer levels were over 1700μ/L, the diagnosis was commonly PE (AUC=0.820). Also, in their study, the diagnosis of CAP was made by C-XR (24).…”

Section: Discussionmentioning

confidence: 99%

The prognostic and diagnostic value of plasma D-dimer levels in elderly patients with community-acquired pneumonia

BULUT¹

2022

tjgeri

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“…For their part, Varol et al found that if D-dimer levels were over 1700μ/L, the diagnosis was commonly PE (AUC=0.820). Also, in their study, the diagnosis of CAP was made by C-XR (24).…”

Section: Discussionmentioning

confidence: 99%

The prognostic and diagnostic value of plasma D-dimer levels in elderly patients with community-acquired pneumonia

BULUT¹

2022

tjgeri

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“…Kanser hastalarında özellikle ileri evrede, venöz tromboembolizm yokken bile hemostatik aktivasyona bağlı hiperkoagülasyon ve fibrinoliz artışı sıklıkla gözlenir 8 . Plazma D-dimerleri endojen fibrinolitik sistemin fibrini yıkması ile oluşur ve koagülasyon aktivitesini günümüzde en iyi gösteren laboratuvar belirteçtir 9 . Yapılan çalışmalar, plazma D-dimer düzeylerinin çeşitli kanser türlerinde tümör evresi ve prognozu ile ilişkili olduğunu ileri sürmektedir 10,11 .…”

Section: Plazma D-dimer Düzeyinin Yüksek Dereceli Seröz Over Kanseri ...unclassified

The Relationship between Plasma D-Dimer Level and Prognostic Factors in Cases with High-Grade Serous Ovarian Cancer

ÖZKAN

Kadıoğlu

Timur

et al. 2022

Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi

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Over kanseri jinekolojik kanserler arasında kansere bağlı ölümlerin önde gelen nedenidir. Kanser hastalarında özellikle ileri evrede, venöz tromboembolizm yokken bile hemostatik aktivasyona bağlı hiperkoagülasyon ve artmış fibrinoliz sıklıkla gözlenir. Bu çalışma ile yüksek dereceli seröz karsinom olgularında operasyon öncesi ölçülen plazma d-dimer düzeyinin klinik önemi ve prognostik değerini incelemeyi amaçladık. Retrosptektif olarak yapılan çalışmamızda Dr. Zekai Tahir Burak Eğitim ve Araştırma Hastanesi Jinekolojik Onkoloji Kliniği’nde 2013-2017 tarihleri arasında primer yüksek dereceli seröz over kanseri (HGSK) tanısı alan ve operasyondan önceki 15 gün içinde D-dimer testi yapılan 142 hasta dahil edildi. Tanı anındaki yaş, tedavi öncesi plazma D-dimer düzeyi, asit varlığı, rezidüel tümör, CA125 seviyesi, FIGO evresi ve demografik bilgileri karşılaştırıldı. Ortalama yaşları 55.25 ±10.84 olan hastaların 52’ sinde (%36,6) normal, 90’ ında(%63,4) D-dimer seviyeleri yüksek olarak saptandı. D-dimer düzeyi yüksek olan ve olmayan olgularda 60 yaş sınır alındığında anlamlı farklılık saptanmazken, D-dimer düzeyi yüksek olan olgularda FIGO evresi (III-IV) daha yüksek olup (p

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Interrelation between markers of system of hemostasis and hemocoagulation disorders in patients with tuberculosis of respiratory organs and comorbid diabetes mellitus after surgical intervention on respiratory organs

Chitorelidze

Валерьевич²,

Serebryanaya

et al. 2020

I.P. Pavlov Russian Medical Biological Herald

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The relevance of the work is determined by the necessity to study markers of coagulation system of blood and hemocoagulation disorders in patients with pulmonary tuberculosis and comorbid diabetes mellitus in different stages of postoperative period. Aim. To determine the interrelation between markers of system of hemostasis and signs of development of intravascular blood coagulation in patients with pulmonary tuberculosis and comorbid diabetes mellitus (TB-DM) depending on the volume of surgical intervention on the respiratory organs. Materials and Methods. The extent of changes of markers of the system of hemostasis was determined in 89 patients with TB-DM before and after surgical treatment. Parameters of coagulation system of blood: concentration of fibrinogen, the level of soluble fibrin-monomer complexes, compensatory potentials by the level of fibrinolysis, activity of fibrinolytic system and of anticoagulation system (antithrombin III) were determined; parameters of prothrombin activity were studied. Besides, operation material of lungs was prepared for morphological examination. Results. A general tendency to increase in the parameters of hypercoagulation syndrome was identified in all the study groups starting from the 3rd-5th day and reaching maximum on the 7th-10th and 14th-17th days of the postoperative period, with compensatory activation of fibrin-stabilizing factor and of fibrinolytic system. Changes in the markers of hemostasis were most prominent in the group of patients after lobectomy. Microthrombotic lesions of the vessels of pulmonary microcirculation with partial or complete obturation of the lumen were morphologically visualized. Conclusion. On the basis of the data obtained a conclusion can be made about the existence of pronounced hypercoagulation syndrome with phenomena of intravascular coagulation of blood in this category of patients, which evidently requires timely prevention and treatment of thromboembolic complications. The results obtained may be used for development of measures aimed at prevention of hemocoagulation complications in patients with TB-DM after the conducted surgical treatment.

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The role of quantitative D-dimer levels in the follow-up and differential diagnosis of pulmonary thromboembolism and community-acquired pneumonia

Cited by 5 publications

References 24 publications

The prognostic and diagnostic value of plasma D-dimer levels in elderly patients with community-acquired pneumonia

The prognostic and diagnostic value of plasma D-dimer levels in elderly patients with community-acquired pneumonia

The Relationship between Plasma D-Dimer Level and Prognostic Factors in Cases with High-Grade Serous Ovarian Cancer

Interrelation between markers of system of hemostasis and hemocoagulation disorders in patients with tuberculosis of respiratory organs and comorbid diabetes mellitus after surgical intervention on respiratory organs

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