The role of psychological factors in response to treatment in neurocardiogenic (vasovagal) syncope

Gracie, J. Alastair; Newton, Julia L.; Norton, Michael; Baker, Christine; Freeston, Mark H.

doi:10.1093/europace/eul073

Cited by 52 publications

(67 citation statements)

References 35 publications

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“…On the other hand, we and others find that the presence of higher levels of general psychological complaints is associated with an increased risk of syncopal recurrence [8,13]. In our study, the association between general psychological complaints and syncopal recurrence remained significant, also if other potential predictors of syncopal recurrence were taken into account.…”

Section: Main Findingssupporting

confidence: 56%

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Association between psychological complaints and recurrence of vasovagal syncope

et al. 2011

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Section: Main Findingssupporting

confidence: 56%

“…Additionally, in several studies, syncopal recurrence was strongly associated with the number of previous syncopal episodes [2,24]. Syncopal recurrence was also found to be associated with age [7,24] and/or gender [2,24], in some, though not all studies [8,12,13].…”

Section: Introductionmentioning

confidence: 96%

Association between psychological complaints and recurrence of vasovagal syncope

et al. 2011

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“…9,11 In previous studies, QoL has been evaluated only once after treatment initiation, in combined groups of patients with various diagnoses and treatments. 10,12,13,27 In contrast, we prospectively evaluated QoL at consecutive time points during follow-up in a more homogeneous group of patients. We found that both the Physical Component Summary of the SF-36 questionnaire and the SDS significantly improved during treatment including physical counterpressure manoeuvres.…”

Section: Discussionmentioning

confidence: 99%

Prospective evaluation of non-pharmacological treatment in vasovagal syncope

et al. 2010

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AimsInitial treatment of vasovagal syncope (VVS) consists of assuring an adequate fluid and salt intake, regular exercise and application of physical counterpressure manoeuvres. We examined the effects of this non-pharmacological treatment in patients with frequent recurrences. Methods and resultsOne hundred patients with 3 episodes of VVS in the 2 years prior to the start of the study openly received nonpharmacological treatment. We evaluated this treatment both with respect to syncopal recurrences, factors associated with recurrence, and quality of life (QoL). The median number of syncopal recurrences was lower in the first year of non-pharmacological treatment compared with the last year before treatment (median 0 vs. 3; P , 0.001), but 49% of patients experienced at least one recurrence. In multivariable analysis, a higher syncope burden prior to inclusion was significantly associated with syncopal recurrence. Disease-specific QoL improved over time, with larger improvements for patients with more reduction in syncope burden. ConclusionIn patients with frequent recurrences of VVS, non-pharmacological treatment has a beneficial effect on both syncopal recurrence and QoL, but nearly half of these patients still experience episodes of syncope.--

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“…More focused and multidisciplinary approaches may be required among these individuals, 37 which might include psychiatric evaluation and intervention. 3,38 However, further research is warranted to examine in detail why this association between syncope and detrimental effects on occupational safety and employment occurs and to facilitate better understanding of the content and organization of preventive strategies.…”

Section: Discussionmentioning

confidence: 99%

Syncope and Its Impact on Occupational Accidents and Employment

Numé

Kragholm

Carlson

et al. 2017

Circ: Cardiovascular Quality and Outcomes

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Background— First-time syncopal episodes usually occur in adults of working age, but their impact on occupational safety and employment remains unknown. We examined the associations of syncope with occupational accidents and termination of employment. Methods and Results— Through linkage of Danish population-based registers, we included all residents 18 to 64 years from 2008 to 2012. Among 3 410 148 eligible individuals, 21 729 with a first-time diagnosis of syncope were identified, with a median age 48.4 years (first to third quartiles, 33.0–59.5), and 10 757 (49.5%) employed at time of the syncope event. Over a median follow-up of 3.2 years (first to third quartiles, 2.0–4.5), 622 people with syncope had an occupational accident requiring hospitalization (2.1/100 person-years). In multiple Poisson regression analysis, the incidence rate ratio in the employed syncope population was higher than in the employed general population (1.44; 95% confidence interval [CI], 1.33–1.55) and more pronounced in people with recurrences (2.02; 95% CI, 1.47–2.78). The 2-year risk of termination of employment was 31.3% (95% CI, 30.4%–32.3%), which was twice the risk of the reference population (15.2%; 95% CI, 14.7%–15.7%), using the Aalen–Johansen estimator. Factors associated with termination of employment were age <40 years (incidence rate ratio, 1.48; 95% CI, 1.37–1.59), cardiovascular disease (1.20; 95% CI, 1.06–1.36), depression (1.72; 95% CI, 1.55–1.90), and low educational level (2.61; 95% CI, 2.34–2.91). Conclusions— In this nationwide cohort, syncope was associated with a 1.4-fold higher risk of occupational accidents and a 2-fold higher risk of termination of employment compared with the employed general population.

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The role of psychological factors in response to treatment in neurocardiogenic (vasovagal) syncope

Cited by 52 publications

References 35 publications

Association between psychological complaints and recurrence of vasovagal syncope

Association between psychological complaints and recurrence of vasovagal syncope

Prospective evaluation of non-pharmacological treatment in vasovagal syncope

Syncope and Its Impact on Occupational Accidents and Employment

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