The Role of Poly-glycerol Sebacate/Gelatin Coating Layer on Biological Features and Calcification Rate of 3D Melt-Molded Antibacterial Scaffold for Heart Valve Tissue Engineering

Preclinical in vivo assessment of a cell-free multi-layered scaffold prepared by 3D printing and electrospinning for small-diameter blood vessel tissue engineering in a canine model

“…The topography and physical properties of the lumen can also affect cellular behaviour. 23 The nanostructured surface and nanometer-scale roughness were found to improve EC adhesion and growth. 24,25 Previously, we found that PCL nanofibers forming the innermost layer of a three-layered scaffold can simultaneously inhibit early thrombus formation and accelerate endothelialization compared to commercial ePTFE grafts.…”