“…The role of PET/CT in the assessment of response to therapy, including SCT, has been emphasized [18][19][20][21]. In our recent study analyzing 88 MM patients [10], we demonstrated a significant impact of PET/CT in overall survival curves when patients who achieved partial or complete response to induction therapy were compared with those who showed disease progression. Although patients with baseline PET/CT positive findings (EMD, more than three focal lesions or diffuse involvement) usually show worse survival curves than negative cases, the difference did not reach statistical significance, likely due to a short follow-up.…”