The role of PET imaging in the evaluation of cholangiocarcinoma and gallbladder carcinoma

Anderson, Christopher; Chari, Ravi S.; Delbeke, Dominique; Rice, Michael H.; Pinson, C. Wright

doi:10.1016/s0016-5085(03)84170-7

Cited by 3 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…20 Studies focused on the use of PET imaging for the evaluation of primary GBC have reported sensitivities of 75-100% for the detection of disseminated disease. 21,22 In our cases we could not perform the PET/CT and CA 19-9 due to its unavailability.…”

Section: Discussionmentioning

confidence: 88%

Role of Staging Laparoscopy in Gallbladder Cancer

Sharma

Thapa

2020

Kathmandu Univ. Med. J.

View full text Add to dashboard Cite

Background Preoperative accurate staging of gallbladder cancer is still difficult. A number of patients with gallbladder cancer who undergo laparotomy for curative resection are ultimately found to have unresectable disease. The benefit of staging laparoscopy is its ability to find out the radilogical occult intraperitoneal metastasis and to spare from non-theraputic laparotomy. The role of staging laparoscopy has been extensively studied in hepatobiliary and pancreatic malignancies and found to be useful. But in recent time its utility in biliary cancers is sceptical probably because of the advent of positron emission tomography. However in gallbladder cancer it is still recommended. Objective To identify the utility of staging laparoscopy in gall bladder cancers. Method Hospital based study conducted at Nepalgunj Medical College, Nepal from October 2014 to June 2020. The patients with resectable gallbladder cancers on computed tomography were included. All patients underwent single stage staging laparoscopy. Staging laparoscopy was considered positive if the surface lesions (liver and/or peritoneal deposits) were detected. The surgery was terminated if positive. Patients with negative staging laparoscopy were proceeded with laparotomy. Result Staging laparoscopy was done in 47. The yield of staging laparoscopy was 14 (29.78%) and its accuracy was 58.33% (14/24). Out of 33 (70.21%) with negative staging laparoscopy, 10 (30.3%) had unresectable disease in laparotomy. The yield was higher in locally advanced in comparison to early disease (78.57% Vs 21.42%). Conclusion We recommend routine staging laparoscopy in gallbladder cancer, particularly when the disease is locally advanced.

show abstract

Section: Discussionmentioning

confidence: 88%

Role of Staging Laparoscopy in Gallbladder Cancer

Sharma

Thapa

2020

Kathmandu Univ. Med. J.

View full text Add to dashboard Cite

show abstract

“…Li reported that the combination of enhanced CT and MRI in the diagnosis of cholangiocarcinoma has high sensitivity and specificity, which can provide an imaging basis for clinical diagnosis and treatment (12). In addition, studies have reported the dense accumulation of the nucleotide tracer 18-fluorodeoxyglucose ( 18 F-FDG) in cholangiocarcinoma (13). PET scan combined with FDG accumulation can show cholangiocarcinoma as small as 1 cm of the bile duct, and it is considered that 18 F-FDG-PET and PET/ CT are accurate in evaluating primary tumor, lymph node metastasis, and distant metastasis in patients with intrahepatic cholangiocarcinoma (14,15).…”

Section: Discussionmentioning

confidence: 99%

Intrahepatic cholangiocarcinoma with gastric metastasis misdiagnosed as primary gastric cancer: A case report and literature review

Zhu

Zhai

et al. 2022

Front. Oncol.

View full text Add to dashboard Cite

We describe a case of intrahepatic cholangiocarcinoma with gastric metastasis misdiagnosed as primary gastric cancer. In addition, combined with the literature, we summarized the clinical and imaging features of gastric metastasis of intrahepatic cholangiocarcinoma in order to improve the understanding of the preoperative diagnosis. Positron emission tomography/computed tomography (PET/CT) is accurate in evaluating the primary tumor, lymph node metastasis, and distant metastasis of patients. In addition, immunohistochemical staining can determine the primary site of metastatic adenocarcinoma. For patients who can not determine the location of the primary tumor, the rigorous preoperative examination is necessary, it can improve the accuracy of diagnosis and avoid excessive treatment of patients.

show abstract

“…False-negatives include limited detection of smaller malignant lesions measuring less than 1 cm and tumors with relatively high mucinous content. 58…”

Section: Cholangiocarcinomamentioning

confidence: 99%

Approach to Biliary Malignancies

Lee

Arora

2023

Journal of Gastrointestinal and Abdominal Radiology

View full text Add to dashboard Cite

Biliary malignancies arise from anywhere along the biliary tract and broadly encompass gallbladder cancer and cholangiocarcinoma. Surgical resection with curative intent remains the mainstay treatment for biliary tract malignancies, but despite advances in treatment and management over the years, prognosis remains poor. The majority of patients present with nonspecific clinical symptoms and are diagnosed at late-stage disease when surgical resection is no longer an option. In the minority of patients presenting with early-stage disease, it is particularly important to determine accurate radiological staging and take a multidisciplinary approach to determine patients suitable for curative surgical resection. A range of imaging modalities is often used in combination, each providing complementary information to characterize and stage disease. Gallbladder cancer and cholangiocarcinoma are distinct entities and the approach to each of these will be discussed separately.

show abstract

The role of PET imaging in the evaluation of cholangiocarcinoma and gallbladder carcinoma

Cited by 3 publications

References 0 publications

Role of Staging Laparoscopy in Gallbladder Cancer

Role of Staging Laparoscopy in Gallbladder Cancer

Intrahepatic cholangiocarcinoma with gastric metastasis misdiagnosed as primary gastric cancer: A case report and literature review

Approach to Biliary Malignancies

Contact Info

Product

Resources

About