The role of periodontal treatment associated with photodynamic therapy on the modulation of systemic inflammation in the experimental model of asthma and periodontitis

Murakami-Malaquias-da-Silva, Felipe; Rosa, Ellen Perim; Oliveira, Jessica Gonzaga; Avelar, Isabella Sena; Palma-Cruz, Marlon; Silva, Joao Gabriel Fernandes; Rigonato‐Oliveira, Nicole Cristine; Bussadori, Sandra Kalil; Negreiros, Renata Matalon; Oliveira, Ana Paula Ligeiro de; Lino-dos-Santos-Franco, Adriana; Horliana, Anna Carolina Ratto Tempestini

doi:10.1016/j.pdpdt.2019.101619

Cited by 6 publications

(3 citation statements)

References 41 publications

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“…[ 59 60 ] Although PDT shows promising results, given the problems that refractory cases show, it may not be suitable for all cases. [ 31 61 62 63 64 ]…”

Section: Discussionmentioning

confidence: 99%

Applications of lasers in refractory periodontitis: A narrative review

Varma

AlShayeb

Narayanan

et al. 2020

J Int Soc Prevent Communit Dent

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A BSTRACT Objective: The purpose of the study is to evaluate the various lasers in dentistry and to investigate if it can be used for treatment of refractory periodontitis. Methods: The study followed partially the PRISMA guidelines as it is a narrative review. A number of articles were selected from a period of 1980 to 2020 from databases, PubMed, PubMed central, Cochrane and Scopus. Articles related to the effects of lasers on periodontitis both refractory and aggressive were investigated. Results: After reviewing the literature, 70 articles were found, related to application of lasers in periodontal diseases. Out of the 70, 11 articles pertained to the effect of laser for the treatment of Refractory and inflammatory periodontitis. 5 articles related to experimental animal models, one pertaining to in-vitro and six studies related to in-vivo in human cohorts. Discussion: It was found that lasers if used in controlled parameters by incorporating laser assisted treatment such as Photodynamic therapy and low level laser therapy can be of use as an adjunct therapy for treatment of refractory periodontitis. The use of different wavelengths in the initial and maintenance phase of periodontal disease plays a positive role. The presence of in-vitro and animal model studies is one of the limitation to this study. The available studies have shown marked reduction in inflammation and better clinical and microbiological parameters. The drawback of this study is the limited literature involving laser management for refractory periodontitis in human cohorts. Conclusion: Different wavelengths of laser and choice of laser assisted periodontal treatment plays an important role in the overall progress and prognosis of periodontal disease activity.

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“…[ 59 60 ] Although PDT shows promising results, given the problems that refractory cases show, it may not be suitable for all cases. [ 31 61 62 63 64 ]…”

Section: Discussionmentioning

confidence: 99%

Applications of lasers in refractory periodontitis: A narrative review

Varma

AlShayeb

Narayanan

et al. 2020

J Int Soc Prevent Communit Dent

View full text Add to dashboard Cite

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“…The periodontal therapy (PT) associated with photodynamic therapy (PDT) reduced the expression of TNF-a in gingiva (222). Indocyanine green (ICG)-diode laser-based photothermal therapy (PTT) decreased the expression of IL-1b and MMP-8 (223).…”

Section: Other Therapiesmentioning

confidence: 99%

Immunomodulation in the Treatment of Periodontitis: Progress and Perspectives

Yang

Pang

et al. 2021

Front. Immunol.

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Periodontitis is one of the most common dental diseases. Compared with healthy periodontal tissues, the immune microenvironment plays the key role in periodontitis by allowing the invasion of pathogens. It is possible that modulating the immune microenvironment can supplement traditional treatments and may even promote periodontal regeneration by using stem cells, bacteria, etc. New anti-inflammatory therapies can enhance the generation of a viable local immune microenvironment and promote cell homing and tissue formation, thereby achieving higher levels of immune regulation and tissue repair. We screened recent studies to summarize the advances of the immunomodulatory treatments for periodontitis in the aspects of drug therapy, microbial therapy, stem cell therapy, gene therapy and other therapies. In addition, we included the changes of immune cells and cytokines in the immune microenvironment of periodontitis in the section of drug therapy so as to make it clearer how the treatments took effects accordingly. In the future, more research needs to be done to improve immunotherapy methods and understand the risks and long-term efficacy of these methods in periodontitis.

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Section: Other Therapiesmentioning

confidence: 99%

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The role of periodontal treatment associated with photodynamic therapy on the modulation of systemic inflammation in the experimental model of asthma and periodontitis

Cited by 6 publications

References 41 publications

Applications of lasers in refractory periodontitis: A narrative review

Applications of lasers in refractory periodontitis: A narrative review

Immunomodulation in the Treatment of Periodontitis: Progress and Perspectives

Table_1.docx

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