2020
DOI: 10.21203/rs.3.rs-34333/v1
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The Role of P TEN Protein Phosphatase in Nasopharyngeal Carcinoma: The Ability of TGF-β1 Inducing Migration and Invasion was Inhibited by PTEN Protein Phosphatase through Down-regulating p-P38

Abstract: BackgroundThe phosphatase and tensin homolog gene(PTEN) is a crucial cancersuppressor gene in nasopharyngeal carcinoma(NPC),which encodes the protein i-ncluding lipid phosphatase and protein phosphatase.p-P38 plays a vital role in the development process of cancers.However,whether and how PTEN protein p-hosphatase inhibit p-P38 expression and regulate migration and invasion in nas-opharyngeal carcinoma is still fully elucidated.MethodsThe abilities of migration and invasion were analyzed using Scratch,Transwel… Show more

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