The role of organonickel reagents in organophosphorus chemistry

Aryl group transfer and C–P bond formation in the reaction of organonickel complexes with sodium 3,4,5-triphenyl-1,2-diphospholide

“…The pentane extract was evaporated in vacuum to give 0.43 g (82%) yellow solid of 1-mesityl-3,4,5-triphenyl-1,2-diphosphole (4). 1 H NMR (CDCl 3 , d, ppm, J, Hz): 2.23 (s, 3H, Me), 2.36 (s, 6H, Me), 6.83 (d, 3 J HH = 3.4 Hz, 2H, Ph), 6.93-6.97 (m, 3H, Ph), 7.01 (d, 3 J HH = 5.2 Hz, 5H, Ph), 7.08-7.12 (m, 3H, Ph), 7.14-7.19 (m, 4H, Ph). 31 P{ 1 H} NMR (CDCl 3 , d, ppm, J, Hz): 194.2 (d, 1 J PP = 432.5 Hz), 52.2 (d, 1 J PP = 432.5 Hz).…”

Organophosphorus Azoles Incorporating a Tetra-, Penta-, and Hexacoordinated Phosphorus Atom: NMR Spectroscopy and Quantum Chemistry

“…Phosphorus-containing compounds are reported to be in drugs, insecticides, fungicides, polymer plasticizers and stabilizers, catalysts and components for improvement of lubricating oils’ quality; however, there is more [ 1 , 2 , 3 ]. Organophosphorus complexes have gained widespread acceptance in science and engineering [ 4 , 5 , 6 , 7 ]. However, so far, only a small amount (less than 10%) of the produced phosphorus is spent on the synthesis of organic derivatives.…”

A New family of Sulfamidophosphonates Derivatives: Microwave‐Accelerated Multicomponent Synthesis, Characterization and X‐Ray Crystallographic Study**

“…In the past decade, organophosphorus and derivatives compounds have been of great interest and have found a wide range of applications in the areas of medicinal, industrial chemistry, and agricultural, based on their interesting biological and physical properties, as well as their utility as a synthetic intermediate. [1,4] Especially, α-aminophosphonates compounds exhibit excellent therapeutic and pharmaceutical properties, [5,10] due to their-isosteres with α-amino acids [11,12] such anticancer drugs, [13,14] haptens of catalytic antibodies, [15,16] antifungals, [17] anti-HIV agents, [18] enzymes inhibitors, [19] antiviral, [20,21] antiinflammatory, [22] anti-Alzheimer, [23] antioxidant, [24] antimalarial, [25] and inhibition of carbonic anhydrase. [26,27] The importance of αaminophosphonates is illustrated by the publications of several reviews per year.…”