The Role of Optical Coherence Tomography Angiography in the Diagnosis and Management of Acute Vogt–Koyanagi–Harada Disease

Abstract

OCTA allows high-resolution imaging of inflammatory foci suggestive of choriocapillaris hypoperfusion in acute VKH disease non-invasively. OCTA may be very helpful in the follow-up of such patients.

Optical coherence tomography and optical coherence tomography angiography in uveitis: A review

“…Alternatively, the layers demonstrate hyper‐reflective changes and disruption (Figure E) and undergo atrophy despite treatment . Similar findings have been reported in STB and VKH, where OCTA demonstrated discrete areas of diminished or absent flow suggestive of choriocapillaris hypo‐perfusion (Figure G) …”

“…60 Similar findings have been reported in STB and VKH, where OCTA demonstrated discrete areas of diminished or absent flow suggestive of choriocapillaris hypoperfusion ( Figure 9G). 61,62…”

Distinguishing features of acute Vogt-Koyanagi-Harada disease and acute central serous chorioretinopathy on optical coherence tomography angiography and en face optical coherence tomography imaging

“…In the index study, we have described the differentiating features of VKH and CSC in the acute stage using the non-invasive technique of OCTA and en face OCT. OCTA has been recently shown to be an effective tool to identify the changes at the level of choriocapillaris in acute VKH and in monitoring the disease resolution, recurrence, and persistence in conjunction with clinical examination and other multimodal imaging techniques by our group [17]. In the present study, en face OCTA images in the acute stage of VKH showed multiple dark foci of flow void suggestive of choriocapillaris hypoperfusion which were variable in shape and size (20 eyes; 100%).…”

A rare entity: Sympathetic ophthalmia presumably after blunt trauma to the phthisical eye and optical coherence tomography angiography metrics to monitor response to treatment

“…We were able to confirm this similar finding on a 3 × 3 mm grid. Similar mentions on choroidal vasculature has also been mentioned in cases of VKH and has been mentioned that they are more pronounced during the acute stage of the disease …”

“…Similar mentions on choroidal vasculature has also been mentioned in cases of VKH and has been mentioned that they are more pronounced during the acute stage of the disease. 18 Infrared imaging of the retina and choroid revealed a mottled appearance of the fundus after normalization of the retinal and choroidal thickness. On evaluation of these spots on OCT cross sections, they revealed bumps in the RPE and Bruch's membrane with some causing disorganization of the ellipsoid layer.…”