The role of nutrition and nutraceutical supplements in the treatment of hypertension

Abstract

Vascular biology, endothelial and vascular smooth muscle and cardiac dysfunction play a primary role in the initiation and perpetuation of hypertension, cardiovascular disease and target organ damage. Nutrientgene interactions and epigenetics are predominant factors in promoting beneficial or detrimental effects in cardiovascular health and hypertension. Macronutrients and micronutrients can prevent, control and treat hypertension through numerous mechanisms related to vascular biology. Oxidative stress, inflammation and autoimmune dysfunction initiate and propagate hypertension and cardiovascular disease. There is a role for the selected use of single and component nutraceutical supplements, vitamins, antioxidants and minerals in the treatment of hypertension based on scientifically controlled studies which complement optimal nutrition, coupled with other lifestyle modifications.© 2014 Baishideng Publishing Group Co., Limited. All rights reserved.Key words: Hypertension; Nutrition; Nutritional supplements; Cardiovascular disease; Vascular biology Core tip: Vascular biology and endothelial dysfunction play a primary roles in hypertension and subsequent cardiovascular disease. Micronutrients, macronutrients and optimal nutrition and nutritional supplements can prevent, control and treat hypertension through numerous mechanisms related to vascular biology. These treatments are complementary to drug therapy. Oxidative stress, inflammation and autoimmune dysfunction initiate and propagate hypertension and cardiovascular disease. There is a role for the selected use of single and component nutraceutical supplements, vitamins, antioxidants and minerals in the treatment of hypertension based on scientifically controlled studies which complement optimal nutrition, coupled with other lifestyle modifications.Houston M. The role of nutrition and nutraceutical supplements in the treatment of hypertension. World J Cardiol 2014; 6(2): 38-66 Available from:

Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses

“…In fact nutrient-gene interactions and epigenetics are predominant factors in promoting beneficial or detrimental effects in cardiovascular health and hypertension. Macronutrients and micronutrients can prevent, control and treat hypertension through numerous mechanisms related to vascular biology [8].…”

Aging in blood vessels. Medicinal agents FOR systemic arterial hypertension in the elderly

“…Food and nutrients can prevent, control and treat hypertension through numerous vascular biology mechanisms. The use of a single and/or a multi-compound nutraceutical supplement including vitamins, antioxidants and minerals in the treatment of hypertension is based on scientifically controlled studies to complement the optimal dietary intake and other lifestyle modification (Houston, 2014). Some natural compounds have been found to possibly have potential beneficial effects against hypertension Curcumin and its derivative tetrahidrocurcumin lead to a decrease of blood pressure, peripheral vascular resistance, aortic stiffness and oxidative stress.…”

Immunomodulatory Activity of Biofield Energy Healing Based Herbomineral Formulation in <i>Sprague Dawley</i> Rats: Evidence for Humoral and Cell-Mediated Responses

“…The newly formulated herbomineral formulation, which was a combination of ashwagandha root extract along with trace elements such as zinc chloride, magnesium gluconate hydrate, and sodium selenate for immunomodulatory activity. Each constituent of this formulation commonly used as nutraceutical supplement [8][9][10][11]. Herbomineral formulations are reported to improve the general health by increasing the body's immunity.…”