The Role of Neuroimaging in the Ageing Brain

Abstract

It is of crucial importance to recognize the changes that occur in the brain ageing. Although neuroimaging studies are important tools used in the evaluation of changes in brain ageing mainly through the exclusion of comorbidities and neurodegenerative disorders, their role is still controversial. In this minireview, we discuss the main aspects of brain ageing, the differences between the young and old brain, the neuroimaging techniques and the use of neuroimaging to assess brain age. Differentiating the differences between normal structural and pathological ageing will provide a deeper understanding of the ageing process of the brain and will bring us new perspectives on biomarkers.