The role of Nd as a dopant in Mn3O4NPs on the heat induction of artificial breast tissue due to the irradiation of microwaves

Gaona-Esquivel, Alexa; Hernandez-M, Diana S.; Hernández-Rodríguez, Y.M.; Cigarroa-Mayorga, O.E.

doi:10.1016/j.matchemphys.2022.126822

Cited by 7 publications

(3 citation statements)

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“…Valuable information on this topic is presented by A. Gaona-Esquivel et al, and this study addresses the key role of Nd as a dopant in Mn 3 O 4 NPs (manganese oxide nanoparticles) and its effect on heat induction in artificial breast tissue when subjected to microwave radiation. By delving into the intricacies of this study, we gain insight into the nuanced interactions between nanomaterials and target tissues, particularly in the context of breast cancer therapy [ 62 ].…”

Section: Introductionmentioning

confidence: 99%

Magnetic Resonance Imaging in Breast Cancer Tissue In Vitro after PDT Therapy

Bartusik-Aebisher,

Mytych,

Dynarowicz

et al. 2024

Diagnostics

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Photodynamic therapy (PDT) is increasingly used in modern medicine. It has found application in the treatment of breast cancer. The most common cancer among women is breast cancer. We collected cancer cells from the breast from the material received after surgery. We focused on tumors that were larger than 10 mm in size. Breast cancer tissues for this quantitative non-contrast magnetic resonance imaging (MRI) study could be seen macroscopically. The current study aimed to present findings on quantitative non-contrast MRI of breast cancer cells post-PDT through the evaluation of relaxation times. The aim of this work was to use and optimize a 1.5 T MRI system. MRI tests were performed using a clinical scanner, namely the OPTIMA MR360 manufactured by General Electric HealthCare. The work included analysis of T1 and T2 relaxation times. This analysis was performed using the MATLAB package (produced by MathWorks). The created application is based on medical MRI images saved in the DICOM3.0 standard. T1 and T2 measurements were subjected to the Shapiro–Wilk test, which showed that both samples belonged to a normal distribution, so a parametric t-test for dependent samples was used to test for between-sample variability. The study included 30 sections tested in 2 stages, with consistent technical parameters. For T1 measurements, 12 scans were performed with varying repetition times (TR) and a constant echo time (TE) of 3 ms. For T2 measurements, 12 scans were performed with a fixed repetition time of 10,000 ms and varying echo times. After treating samples with PpIX disodium salt and bubbling with pure oxygen, PDT irradiation was applied. The cell relaxation time after therapy was significantly shorter than the cell relaxation time before PDT. The cells were exposed to PpIX disodium salt as the administered pharmacological substance. The study showed that the therapy significantly affected tumor cells, which was confirmed by a significant reduction in tumor cell relaxation time on the MRI results.

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Section: Introductionmentioning

confidence: 99%

Magnetic Resonance Imaging in Breast Cancer Tissue In Vitro after PDT Therapy

Bartusik-Aebisher,

Mytych,

Dynarowicz

et al. 2024

Diagnostics

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“…For instance, La substitutions have been shown to enhance the saturation magnetization, the magnetocrystalline anisotropy, and the Curie temperature [14][15][16]. Additionally, the controlled doping of these materials can lead to tailored band gaps and enhanced conductivity, further expanding their potential applications in optoelectronics and solid oxide fuel cells [17][18][19][20]. Hence, ion-doped M-type hexaferrites, particularly when doped or modified, stand out as pivotal candidates for a broad spectrum of technological advancements.…”

Section: Introductionmentioning

confidence: 99%

Theoretical Study of Electric, Dielectric, and Optical Properties in Ion Doped Multiferroic SrFe12O19 Nanoparticles

Apostolov,

Apostolova,

Wesselinowa

2024

Materials

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Electric, dielectric, and optical (band gap) properties of pure multiferroic as well as La- and Ni-doped SrFe12O19 (SFO) (at different sites) are investigated using a microscopic model and Green’s function technique. The concentration dependence of the polarization P is considered for substitution of rare earths ions on the Sr sites. For a small La ion doping concentration, x = 0.1, La-doped SFO is ferroelectric, whereas for a larger doping concentration, for example x = 0.5, it is antiferroelectric. The real part of the dielectric constant ϵ increases with an increasing magnetic field h. ϵ decreases with an increasing frequency and La dopants. Therefore, La-doped SFO is suitable for microwave application with a low dielectric constant. The magnetic properties of pure SFO NPs are also studied. Ni doping at the Fe site of SFO leads to enhanced ferroelectric polarization and dielectric constant. The band gap decreases or increases by substitution of Ni or In ions on the Fe site, respectively. The results reveal that the tuned band gap of Ni-doped SFO makes it a crucial candidate for optoelectronic and solid oxide fuel cell applications.

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“…The composition of the nanoparticles used in hyperthermia has been increasing in variety and many NPs are magnetite-based (being bare-naked or functionalized and covered with a specific layer of another material, e.g., citric acid, alginate, etc. ); moreover, lately there has been a focus on the use of ferrites (e.g., Mn-Ferrites [26,27].…”

Section: Introductionmentioning

confidence: 99%

Economic and Accessible Portable Homemade Magnetic Hyperthermia System: Influence of the Shape, Characteristics and Type of Nanoparticles in Its Effectiveness

Castelo-Grande,

Augusto,

Gomes

et al. 2024

Materials

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Currently, one of the main causes of death in the world is cancer; therefore, it is urgent to obtain a precocious diagnosis, as well as boost research and development of new potential treatments, which should be more efficient and much less invasive for the patient. Magnetic hyperthermia (MH) is an emerging cancer therapy using nanoparticles, which has proved to be effective when combined with chemotherapy, radiotherapy and/or surgery, or even by itself, depending on the type and location of the tumor’s cells. This article presents the results obtained by using a previously developed economic homemade hyperthermia device with different types of magnetite nanoparticles, with sizes ranging between 12 ± 5 and 36 ± 11 nm and presenting different shapes (spherical and cubic particles). These magnetic nanoparticles (MNPs) were synthesized by three different methods (co-precipitation, solvothermal and hydrothermal processes), with their final form being naked, or possessing different kinds of covering layers (polyethylene glycol (PEG) or citric acid (CA)). The parameters used to characterize the heating by magnetic hyperthermia, namely the Specific Absorption Rate (SAR) and the intrinsic loss power (ILP), have been obtained by two different methods. Among other results, these experiments allowed for the determination of which synthesized MNPs showed the best performance concerning hyperthermia. From the results, it may be concluded that, as expected, the shape of MNPs is an important factor, as well as the time that the MNPs can remain suspended in solution (which is directly related to the concentration and covering layer of the MNPs). The MNPs that gave the best results in terms of the SAR were the cubic particles covered with PEG, while in terms of total heating the spherical particles covered with citric acid proved to be better.

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The role of Nd as a dopant in Mn3O4NPs on the heat induction of artificial breast tissue due to the irradiation of microwaves

Cited by 7 publications

References 73 publications

Magnetic Resonance Imaging in Breast Cancer Tissue In Vitro after PDT Therapy

Magnetic Resonance Imaging in Breast Cancer Tissue In Vitro after PDT Therapy

Theoretical Study of Electric, Dielectric, and Optical Properties in Ion Doped Multiferroic SrFe12O19 Nanoparticles

Economic and Accessible Portable Homemade Magnetic Hyperthermia System: Influence of the Shape, Characteristics and Type of Nanoparticles in Its Effectiveness

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