The Role of Natural Products from Herbal Medicine in TLR4 Signaling for Colorectal Cancer Treatment
Yan Luo,
Guochen Zhang,
Chao Hu
et al.
Abstract:The toll-like receptor 4 (TLR4) signaling pathway constitutes an intricate network of protein interactions primarily involved in inflammation and cancer. This pathway triggers intracellular signaling cascades, modulating transcription factors that regulate gene expression related to immunity and malignancy. Previous studies showed that colon cancer patients with low TLR4 expression exhibit extended survival times and the TLR4 signaling pathway holds a significant role in CRC pathogenesis. In recent years, trad… Show more
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