Abstract:Objective: to evaluate the role of monitoring the level of matrix metalloproteinase 3 (MMP-3) in patients with rheumatoid arthritis (RA) during anti-B-cell therapy.Material and methods. The study included 54 patients with a reliable diagnosis of RA. Depending on the therapy, all patients were divided into two groups: 34 patients received the original RTM (group 1) and 20 patients – biosimilar (group 2) in a total dose of 1200 mg according to the standard scheme. The concentration of MMP-3 in serum was measured… Show more
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