The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review

Purnamawati, Schandra; Indrastuti, Niken; Danarti, Retno; Saefudin, Tatan

doi:10.3121/cmr.2017.1363

Cited by 214 publications

(220 citation statements)

References 69 publications

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“…Also it should be stressed that both pimecrolimus and tacrolimus have antifungal action against Malassezia yeasts (Sugita et al, 2006) so at least part of their activity in seborrheic dermatitis can be attributed to this. A variety of alternative or natural product treatments are also suggested for seborrheic dermatitis (Gupta and Versteeg, 2017) while a recent suggestion is the use of formulations that restore the barrier function of the skin (Purnamawati et al, 2017) and definitely formulations that restore the barrier function of the skin will be a useful addition to treatment (Wikramanayake et al, 2019). Furthermore various salts are also efficient, like lithium succinate, which seems to interfere with the availability of the prerequisite lipids for Malassezia growth (Mayser and Schulz, 2016).…”

Section: Treatmentmentioning

confidence: 99%

Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment

Saunte

Gaitanis

Hay

2020

Front. Cell. Infect. Microbiol.

127

110

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Yeasts of the genus, Malassezia, formerly known as Pityrosporum, are lipophilic yeasts, which are a part of the normal skin flora (microbiome). Malassezia colonize the human skin after birth and must therefore, as commensals, be normally tolerated by the human immune system. The Malassezia yeasts also have a pathogenic potential where they can, under appropriate conditions, invade the stratum corneum and interact with the host immune system, both directly but also through chemical mediators. The species distribution on the skin and the pathogenetic potential of the yeast varies between different Malassezia related diseases such as head and neck dermatitis, seborrheic dermatitis, pityriasis versicolor, and Malassezia folliculitis. The diagnostic methods used to confirm the presence of Malassezia yeasts include direct microcopy, culture based methods (often a combination of morphological features of the isolate combined with biochemical test), molecular based methods such as Polymerase Chain Reaction techniques, and Matrix Assisted Laser Desorption/Ionization-Time Of Flight mass spectrometry and the chemical imprint method Raman spectroscopy. Skin diseases caused by Malassezia are usually treated with antifungal therapy and if there are associated inflammatory skin mechanisms this is often supplemented by anti-inflammatory therapy. The aim of this paper is to provide an overview of Malassezia related skin disease, diagnostic methods and treatment options.

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Section: Treatmentmentioning

confidence: 99%

Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment

Saunte

Gaitanis

Hay

2020

Front. Cell. Infect. Microbiol.

127

110

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“…Although many topical preparations have been shown to be effective in highly controlled clinical trials, their frequency of use by patients varies dramatically in practice. Unachievable routines and unpleasant smell and consistency are commonly cited reasons for poor adherence (51,57).…”

Section: Topical Management Of Itchmentioning

confidence: 99%

“…Lotions contain more water than lipids; creams contain lipids, water and an emulsifier; and ointments are primarily lipid based (49,51). The most appropriate formulation for the patient can depend on a variety of factors, including season, tolerability, cost, mechanism of action, fragrance, age, body area and gender (51,57,58). For example, emollients targeting the face aim to be noncomedogenic (64,65).…”

Section: Emollientsmentioning

confidence: 99%

Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions

Yosipovitch¹,

Miséry²,

Proksch³

et al. 2019

Acta Derm Venereol

112

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Itch is a common symptom of many skin barrier-related dermatoses and can severely impact quality of life. However, there are a limited number of effective anti-itch topical therapies currently available and several unmet needs not addressed by current itch management strategies. As our knowledge of the mechanisms underlying itch has improved, several novel therapies have recently emerged that can be incorporated into existing regimens to enhance itch therapy and management. Here, we summarise research and current opinion on available topical therapies and give recommendations for the optimal management of itch. Barrier damage, dry skin and itch are intricately linked and form the basis of many common skin diseases. Damage from environmental insults, or genetic or inflammatory causes, can impair the skin barrier, resulting in an increase in transepidermal water loss and activation of itch-associated nerve fibres. The itch-scratch cycle can perpetuate skin barrier damage and itch. Topical therapeutic strategies are utilised to overcome dry skin and itch, primarily in the form of emollients. Recent advances in our understanding of the mechanisms underlying itch have enabled the development of new topical therapies, which may be incorporated into existing treatment regimes. Ultimately, treatment of dry skin and itch must be highly tailored to the individual according to their needs.

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“…Collagen is being investigated for its potential use in the biomedical field as biomaterials for biomedical or pharmaceutical applications. Collagen is also used as a moisturizer and natural humectant in cosmetic formulations (Purnamawati, et al, 2017). Collagen, which is a high-molecular weight protein, cannot be absorbed by the stratum corneum of the skin and thus remains on the skin surface and acts as a water-uptake through hydration to keep the skin moisturized (Yong et al, 2004) and as protector against microbial infiltration in cases of wounded tissue (Chattopadhyay and Raines , 2014).…”

Section: Active Ingredients For Moisturizermentioning

confidence: 99%

The Potential of Marine Resources in Cosmetics

Alparslan¹,

Şekeroğlu

Kijjoa³

2018

Current Perspectives on Medicinal and Aromatic Plants (CUPMAP)

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The Ocean is a continuous body of saltwater that covers more than 70 percent of the Earth's surface. Despite the fact that oceanic habitats exhibit chemical and physical properties that make certain ocean zones suitable or unsuitable places for different species to live, the chemical (salinity and dissolved gases) and physical (temperature, density, buoyancy, waves, tides, and currents) properties of ocean water are delicately intermingled which produce one of the most self-sustaining life support systems on earth. This unique characteristic has made the marine environment an untapped source of bioactive natural products with unique structural and chemical features. Although many marine-derived compounds have been explored for their potential in pharmaceutical industry and some of which are already on the market, these molecules are still underexplored for natural cosmetics when compared to plant-derived compounds. However, recently many cosmetic firms have turned their attention to the sea to obtain several kinds of marine-derived compounds for cosmetic ingredients such as moisturizer, anti-ageing, photoprotection and skin whitening agents. With more research on the small molecules, biopolymers and enzymes from the marine environment, it is expected that the era of "blue cosmetics" will be dominating this sector very soon.

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The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review

Cited by 214 publications

References 69 publications

Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment

Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment

Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions

The Potential of Marine Resources in Cosmetics

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