The role of moderate static magnetic fields on biomineralization of osteoblasts on sulfonated polystyrene films

Osteogenic differentiation of MC3T3-E1 cells on poly(l-lactide)/Fe3O4 nanofibers with static magnetic field exposure

“…On one hand, the results suggested that the SMF in strength of 100 mT had little cytotoxicity to MC3T3-E1 cells. Our findings were consistent with previous studies that osteoblasts demonstrated an enhanced proliferation on non-magnetic substrates when exposed to moderate SMFs [27]. And the magnetic feature of PLLA/Fe 3 O 4 composite nanofibers in exterior SMF could stimulate cell proliferation to an even higher extent.…”

“…Fractional exposure study revealed that SMF at the early stage of culture was rather effective in promoting osteogenic differentiation [9]. It was reported that application of a 150 mT SMF on murine MC3T3-E1 osteoblasts induced the increase of osteocalcin secretion after 15 days culture [27]. And our results suggested that higher content of MNPs in scaffold, which resulted in stronger magnetism in a fixed SMF, was more beneficial for osteogenic differentiation.…”

A Preliminary Study of the Effect of Static Magnetic Field Acting on Rat Bone Marrow Mesenchymal Stem Cells during Osteogenic Differentiation In Vitro

“…Since SMF has been shown to be effective in facilitating ununited fracture repair 16) and preventing bone loss 17) , it has received considerable attention about the biological effect of SMF on bone cells. A certain intensity SMF has been reported that it can significantly enhance osteoblast differentiation in vitro [18][19][20] . 25) , and in our study BMP-2 was reactive to SMF exposure with a maximized increasing on day 5 over control group in the protein expression before the mineralization occurred differently in the two groups.…”

Magnetoactive electrospun nanofibers in tissue engineering applications

“…X. Ba et al (2011) reported on the enhanced proliferation of osteoblasts under moderate static magnetic fields (SMFs) on magnetic-free scaffolds [122]. The authors stated that even in the presence of moderate SMF osteogenic differentiation an activity of the osteoblasts is promoted.…”