The role of miRNA- 96 and miRNA-150 between different BCR-ABL p210 transcript levels and between different levels of imatinib optimal response in CML patients

Radhi, Kawthar Ali; Matti, Bassam Francis; Hamzah, Israa Hussein

doi:10.1016/j.humgen.2023.201166

Cited by 1 publication

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“…These genes may be found in the genome's coding or non-coding sections (Gullotta, Korte, & Marquardt, 2023). has attracted the most attention among miRNAs because of its role in a number of clinical processes and its influence on how drugs respond (Radhi, Matti, & Hamzah, 2023;Taheri et al, 2022). Numerous human ailments, including cancer, neurological issues, and cardiovascular conditions have been linked to miRNA-96 (Suzuki, 2023).…”

Section: Introductionmentioning

confidence: 99%

A New Insight of MicroRNA-96 In Human Malignant Disorders and Drug Resistance

2023

QZJ

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Autumn2023miRNA-96 is a short non-coding RNA molecule which plays an essential function in the regulation of post-transcriptional gene, and play a role in the development of a number of illnesses, such as cancer, depending on the cellular setting, it may function as a tumor suppressor or an oncogene. According to a recent research, miRNA-96 levels has been decreased in gastric cancer, breast cancer, pancreatic cancer, renal cancer and cervical cancer. However, the levels of miRNA-96 in several kinds of cancers are increased, including colorectal, lung, prostate, glioma, osteosarcoma, and hepatocellular carcinoma. The current review aims to offer a summary of miRNA-96's role in the advancement of cancer illnesses and with an emphasis on dysregulated signaling pathways. Based on in vivo, in vitro, and human research, we also go over the function of this miRNA-96 as a cancer biomarker of prognosis and emphasize how it contributes to drug resistance.

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Section: Introductionmentioning

confidence: 99%

A New Insight of MicroRNA-96 In Human Malignant Disorders and Drug Resistance

2023

QZJ

View full text Add to dashboard Cite

show abstract

The role of miRNA- 96 and miRNA-150 between different BCR-ABL p210 transcript levels and between different levels of imatinib optimal response in CML patients

Cited by 1 publication

References 25 publications

A New Insight of MicroRNA-96 In Human Malignant Disorders and Drug Resistance

A New Insight of MicroRNA-96 In Human Malignant Disorders and Drug Resistance

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