Abstract:Background:
Heart failure with preserved ejection fraction (HFpEF) is associated with increased risk
for hospitalization and all-cause mortality. Currently, there is no established treatment to improve the survival of
these patients. Aldosterone appears to play a role in the pathogenesis of HFpEF.
Objective:
To discuss the findings of studies that evaluated the effects of mineralocorticoid receptor (MR) antagonists
on the outcome of patients with HFpEF.
Methods:
PubMed was searched for relevant papers. Ref… Show more
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