The role of microbiota in gastric cancer: A comprehensive review

Abstract

BackgroundGastric cancer (GC) continues to pose a significant global threat in terms of cancer‐related fatalities. Despite notable advancements in medical research and therapies, further investigation is warranted to elucidate its underlying etiology and risk factors. Recent times have witnessed an escalated emphasis on comprehending the role of the microbiota in cancer development.MethodsThis review briefly delves into recent developments in microbiome‐related research pertaining to gastric cancer.ResultsAccording to studies, the microbiota can influence GC growth by inciting inflammation, disrupting immunological processes, and generating harmful microbial metabolites. Furthermore, there is ongoing research into how the microbiome can impact a patient's response to chemotherapy and immunotherapy.ConclusionThe utilization of the microbiome for detecting, preventing, and managing stomach cancer remains an active area of exploration.