The Role of Mesenchymal Stromal Cells in the Treatment of Rheumatoid Arthritis
Estera Bakinowska,
Aleksandra Wiktoria Bratborska,
Kajetan Kiełbowski
et al.
Abstract:Rheumatoid arthritis (RA) is a chronic inflammatory joint disease characterised by the formation of a hyperplastic pannus, as well as cartilage and bone damage. The pathogenesis of RA is complex and involves broad interactions between various cells present in the inflamed synovium, including fibroblast-like synoviocytes (FLSs), macrophages, and T cells, among others. Under inflammatory conditions, these cells are activated, further enhancing inflammatory responses and angiogenesis and promoting bone and cartil… Show more
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