The Role of Membrane‐Tethered Mucins in Axial Epithelial Adhesion in Controlled Normal Stress Environments
Philipp Baumli,
Chunzi Liu,
Aleksandar Bekčić
et al.
Abstract:The collective adhesive behavior of epithelial cell layers mediated by complex macromolecular fluid environments plays a vital role in many biological processes. Mucins, a family of highly glycosylated proteins, are known to lubricate cell‐on‐cell contacts in the shear direction. However, the role of mucins mediating axial epithelial adhesion in the direction perpendicular to the plane of the cell sheet has received less attention. This article subjects cell‐on‐cell layers of live ocular epithelia that express… Show more
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