The role of long non-coding RNA HCG18 in cancer

Wang, Zhiqiang; Ran, Ruiqiong; Zhang, Shunbai; Wen-ming, Zhou; Lv, Jiayang; Ma, Chun-Wei; Hai-hong, Zhang

doi:10.1007/s12094-022-02992-8

Cited by 5 publications

(1 citation statement)

References 80 publications

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“…The expressions of some lncRNAs that vary according to tissues show high specificity, sensitivity, and accuracy when these lncRNAs are evaluated together with helper biomarkers. Examples of the use of lncRNAs for both diagnosis and prognosis in the early diagnosis and treatment of various types of cancer were reported [ 33 , 34 ]. LncRNAs that play roles in diagnosis and prognosis in different tissues are given in Figure 1 .…”

Section: Lncrnas In Cancermentioning

confidence: 99%

Long noncoding RNAs in pancreas cancer: from biomarkers to therapeutic targets

TANOĞLU,

ADIGÜZEL,

TANOĞLU

et al. 2023

Turkish Journal of Medical Sciences

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Long noncoding RNAs (lncRNAs) are noncoding RNA molecules with a heterogeneous structure consisting of 200 or more nucleotides. Because these noncoding RNAs are transcribed by RNA polymerase II, they have properties similar to messenger RNA (mRNA). Contrary to popular belief, the term “ncRNA” originated before the discovery of microRNAs. LncRNA genes are more numerous than protein-coding genes. They are the focus of current molecular research because of their pivotal roles in cancer-related processes such as cell proliferation, differentiation, and migration. The incidence of pancreatic cancer (PC) is increasing around the world and research on the molecular aspects of PC are growing. In this review, it is aimed to provide critical information about lncRNAs in PC, including the biological and oncological behaviors of lncRNAs in PC and their potential application in therapeutic strategies and as diagnostic tumor markers.

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Section: Lncrnas In Cancermentioning

confidence: 99%