The role of lifestyle factors on comorbidity of chronic liver disease and cardiometabolic disease in Chinese population: A prospective cohort study

Pang, Yuanjie; Han, Yuting; Yu, Canqing; Kartsonaki, Christiana; Guo, Yu; Yang, Ling; Du, Huaidong; Hou, Wei; Schmidt, Danile; Stevens, Rebecca; Chen, Junshi; Chen, Zhengming; Lv, Jun; Li, Liming

doi:10.1016/j.lanwpc.2022.100564

Cited by 2 publications

(2 citation statements)

References 33 publications

(41 reference statements)

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“…Many studies have emphasized the role of weight control on regression of chronic liver disease (54).…”

Section: Negligence Of Obesity and Bmi Control In Patients With Liver...mentioning

confidence: 99%

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Iatrogenic liver diseases: a new concept, with practices to be condemned

Elsabaawy,

Alhaddad

2023

Preprint

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After years and years of practicing hepatology, one can had a panoramic view analysing objectively the performance of hepatologists and the most common misjudges which might lead to a more catastrophic insults to an already diseased liver. Iatrogenic liver insults in patients with liver diseases (either acute or chronic) extends extremely beyond what is known as drug induced liver injury. Lack of nutritional instructions according to the disease category, the incorrectly recommended hypomobility, and lack of screening of hepatocellular carcinoma, oesophageal varices, sarcopenia, and minimal hepatic encephalopathy, diabetes mellitus, added to fibrosis progression and cirrhosis decompensation, are all considered as an aggressive forms of iatrogenic liver diseases (ILD). Additionally, negligence of the bad impacts of obesity on provoking liver cirrhosis morbidities and mortality. The continuous improper use of proton pump inhibitors also represented a major challenge in those patients with a wide diversity of complications. These frequent forms of hepatologists’ malpractice had to be denounced and corrected. “Iatrogenic liver diseases” is a new terminology had to be indorsed deeply in most hepatologists’ ethos on dealing with chronic liver disease patients to alleviate the burden of unintentionally aggravated liver disorders.

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“…Many studies have emphasized the role of weight control on regression of chronic liver disease (54).…”

Section: Negligence Of Obesity and Bmi Control In Patients With Liver...mentioning

confidence: 99%

“…Dietary and physical regimens are the only reproductive measures for obesity control in patients with liver cirrhosis either compensated or non-compensated (54). Importantly, bariatric surgery could be the last resort to cirrhotic patients with morbid obesity.…”

Section: Negligence Of Obesity and Bmi Control In Patients With Liver...mentioning

confidence: 99%

Iatrogenic liver diseases: a new concept, with practices to be condemned

Elsabaawy,

Alhaddad

2023

Preprint

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Effectiveness of a socioecological model-guided, smart device-based, self-management-oriented lifestyle intervention in community residents: protocol for a cluster-randomized controlled trial

Yang,

Yu,

Liao

et al. 2024

BMC Public Health

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Background Healthy lifestyles are crucial for preventing chronic diseases. Nonetheless, approximately 90% of Chinese community residents regularly engage in at least one unhealthy lifestyle. Mobile smart devices-based health interventions (mHealth) that incorporate theoretical frameworks regarding behavioral change in interaction with the environment may provide an appealing and cost-effective approach for promoting sustainable adaptations of healthier lifestyles. We designed a randomized controlled trial (RCT) to evaluate the effectiveness of a socioecological model-guided, smart device-based, and self-management-oriented lifestyles (3SLIFE) intervention, to promote healthy lifestyles among Chinese community residents. Methods This two-arm, parallel, cluster-RCT with a 6-month intervention and 6-month follow-up period foresees to randomize a total of 20 communities/villages from 4 townships in a 1:1 ratio to either intervention or control. Within these communities, a total of at least 256 community residents will be enrolled. The experimental group will receive a multi-level intervention based on the socioecological model supplemented with a multi-dimensional empowerment approach. The control group will receive information only. The primary outcome is the reduction of modifiable unhealthy lifestyles at six months, including smoking, excess alcohol consumption, physical inactivity, unbalanced diet, and overweight/obesity. A reduction by one unhealthy behavior measured with the Healthy Lifestyle Index Score (HLIS) will be considered favorable. Secondary outcomes include reduction of specific unhealthy lifestyles at 3 months, 9 months, and 12 months, and mental health outcomes such as depression measured with PHQ-9, social outcomes such as social support measured with the modified Multidimensional Scale of Perceived Social Support, clinical outcomes such as obesity, and biomedical outcomes such as the development of gut microbiota. Data will be analyzed with mixed effects generalized linear models with family and link function determined by outcome distribution and accounting for clustering of participants in communities. Discussion This study will provide evidence concerning the effect of a mHealth intervention that incorporates a behavioral change theoretical framework on cultivating and maintaining healthy lifestyles in community residents. The study will provide insights into research on and application of similar mHealth intervention strategies to promote healthy lifestyles in community populations and settings. Trial registration number ChiCTR2300070575. Date of registration: April 17, 2023. https://www.chictr.org.cn/index.aspx.

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The role of lifestyle factors on comorbidity of chronic liver disease and cardiometabolic disease in Chinese population: A prospective cohort study

Cited by 2 publications

References 33 publications

Iatrogenic liver diseases: a new concept, with practices to be condemned

Iatrogenic liver diseases: a new concept, with practices to be condemned

Effectiveness of a socioecological model-guided, smart device-based, self-management-oriented lifestyle intervention in community residents: protocol for a cluster-randomized controlled trial

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