The role of L-arginine in the pathogenesis of essential arterial hypertension
V. A. Shcherbak,
A. S. Medvedeva,
T. A. Aksenova
et al.
Abstract:The role of arginine in the development of primary arterial hypertension continues to be clarified up to the present moment. During natural metabolic processes in cells, methylated forms of arginine are produced – symmetric (SDMA) and asymmetric (ADMA) dimethylarginine. ADMA is a nitric oxide synthase inhibitor and is now considered a well-established marker for endothelial dysfunction. SDMA is not a nitric oxide synthase inhibitor, but may indirectly reduce nitric oxide production through competitive interact… Show more
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