The role of juvenile hormone in immune function and pheromone production trade-offs: a test of the immunocompetence handicap principle

Rantala, Markus J.; Vainikka, Anssi; Kortet, Raine

doi:10.1098/rspb.2003.2472

Cited by 181 publications

(169 citation statements)

References 32 publications

Supporting

Mentioning

153

Contrasting

Unclassified

Order By: Relevance

“…Proximately, insect juvenile hormone (JH) is secreted with mating activity. JH is antagonistic to PO activity in tenebrionid beetles (Rolff & Siva-Jothy, 2002), but it enhances male attractiveness (Rantala et al ., 2003b). Whether males augment JH at the expense of PO in migratory Mormon crickets is not known.…”

Section: Discussionmentioning

confidence: 99%

Immediate protein dietary effects on movement and the generalised immunocompetence of migrating Mormon crickets Anabrus simplex (Orthoptera: Tettigoniidae)

Srygley

Lorch

Simpson

et al. 2009

Ecological Entomology

View full text Add to dashboard Cite

Abstract. 1. Mormon crickets form large migratory bands that march over rangeland in the western United States seeking salt and protein. Immune defence is particularly relevant to survival in migratory bands, but little is known about the role of nutrition in insect immunocompetence. We hypothesised that immune defences are compromised in these migratory bands due to nutrient limitations.2. In a migratory band in Utah, we investigated whether access to a protein relative to a carbohydrate diet would immediately reduce migratory activity, as had been shown for Mormon crickets in a previous study in Idaho, and whether the protein diet would enhance immune defence responses.3. Radio-tracking Mormon crickets in the field, we found that locomotor activity was significantly and positively associated with body mass. Body mass-adjusted locomotor activity declined marginally following access to a protein diet, whereas spontaneous phenoloxidase (PO) activity was enhanced by the same diet. The encapsulation response and lysozyme-like activity were directly proportional to body mass, but unaffected by the dietary treatments in the short term. Within 6 h of feeding on protein or carbohydrates, Mormon crickets exhibited measurable effects on the immune system. 4. We conclude that nutrition impacts immune function in migrating insects in the field. Spontaneous PO activity may be limited by dietary deficiency in a proteinseeking band of Mormon crickets.

show abstract

Section: Discussionmentioning

confidence: 99%

Immediate protein dietary effects on movement and the generalised immunocompetence of migrating Mormon crickets Anabrus simplex (Orthoptera: Tettigoniidae)

Srygley

Lorch

Simpson

et al. 2009

Ecological Entomology

View full text Add to dashboard Cite

show abstract

“…The signalling immunocompetence hypothesis predicts a positive correlation between immunity and the expression of secondary sexual traits. However, some studies have failed to find any such relationship [13], or, even more perplexing, have found contrasting relationships between sexually selected traits and immune measures [12]. Thus, a recurrent challenge in ecoimmunology is determining how to interpret the often contradictory results attained when studying multiple immune parameters.…”

Section: Introductionmentioning

confidence: 99%

Sex-biased immunity is driven by relative differences in reproductive investment

Vincent

Gwynne

2014

Proc. R. Soc. B.

View full text Add to dashboard Cite

Sex differences in immunity are often observed, with males generally having a weaker immune system than females. However, recent data in a sexrole-reversed species in which females compete to mate with males suggest that sexually competitive females have a weaker immune response. These findings support the hypothesis that sexual dimorphism in immunity has evolved in response to sex-specific fitness returns of investment in traits such as parental investment and longevity, but the scarcity of data in sexreversed species prevents us from drawing general conclusions. Using an insect species in which males make a large but variable parental investment in their offspring, we use two indicators of immunocompetence to test the hypothesis that sex-biased immunity is determined by differences in parental investment. We found that when the value of paternal investment was experimentally increased, male immune investment became relatively greater than that of females. Thus, in this system, in which the direction of sexual competition is plastic, the direction of sex-biased immunity is also plastic and appears to track relative parental investment.

show abstract

“…However, an aspect that has been scarcely studied is the effect of JH upon the immune response. For example in Tenebrio molitor [10] and Calopteryx virgo [11], the application of JH III or methoprene (JHa; an analogue of JH) respectively, diminished the production of Phenoloxidase (PO). This is a key enzyme for both the humoral (melanization) and cellular (encapsulation) response against pathogens, as well as wound repair and clotting after injury [12,13].…”

Section: Introductionmentioning

confidence: 99%

“…There are two hypotheses that may explain why the JH is not a general immune suppressor: a) some but not all immune markers could be affected in the same way [10] and/or b) it affects differentially males and females, and at the same time, their respective immune response levels. On the one hand, the first explanation predicts that controlling for the JH doses, some immune markers should decrease, while others could be increased or not be affected.…”

Section: Introductionmentioning

confidence: 99%

In the monarch butterfly the juvenile hormone effect upon immune response depends on the immune marker and is sex dependent

Villanueva¹,

Lanz‐Mendoza²,

Hernández‐Martínez³

et al. 2013

OJE

View full text Add to dashboard Cite

In insects, juvenile hormone (JH) decreases or has any effect upon the phenoloxidase (PO) activity, and favors or decreases the Antimicrobial Peptides (AMPs) expression. Although there is no information about the differential effect of such hormone, two possibilities are that it depends on (a) the immune marker recorded and (b) sexual differences. Here, three commonly used immune markers, Phenoloxidase (PO), hydrogen peroxide (H 2 O 2 ), and lytic activity, were measured 3, 6 and 24 hours after administration of methoprene (JHa, an analog of juvenile hormone) in male and female monarch butterflies (Danaus plexippus). At 3 and 6 h post-JHa administration, the PO activity increased in females but it only increased at 3 h in males, whereas H 2 O 2 levels increased only in females at 3 h. For the remaining times the JHa had a null effect on PO and H 2 O 2 . On the other hand, the JHa had a null effect for lytic activity in both sexes at 3, 6 and 24 h. To our knowledge, this is the first report of a positive effect of a JHa on PO and H 2 O 2 and suggests that this effect is sex dependent.

show abstract

The role of juvenile hormone in immune function and pheromone production trade-offs: a test of the immunocompetence handicap principle

Cited by 181 publications

References 32 publications

Immediate protein dietary effects on movement and the generalised immunocompetence of migrating Mormon crickets Anabrus simplex (Orthoptera: Tettigoniidae)

Immediate protein dietary effects on movement and the generalised immunocompetence of migrating Mormon crickets Anabrus simplex (Orthoptera: Tettigoniidae)

Sex-biased immunity is driven by relative differences in reproductive investment

In the monarch butterfly the juvenile hormone effect upon immune response depends on the immune marker and is sex dependent

Contact Info

Product

Resources

About