Abstract:The proliferation of human embryonic and adult stem cells is controlled by extrinsic factors such as epidermal growth factor (EGF) and fibroblast growth factor (bFGF). Their differentiation, instead, is clearly determined by a family of neuropoietic factors including ciliary neurotrophic factor (CNTF), leukaemia inhibitory factor (LIF) and interleukin-6 (IL-6). The results of this study show the capability of the interleukin-6 to delay the differentiation processes and to improve significantly the proliferatio… Show more
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