The role of image-guided therapy in the management of colorectal cancer metastatic disease

Baère, Thierry De; Tselikas, Lambros; Yevich, Steven; Boige, Valérie; Deschamps, Frédèric; Ducreux, Michel; Goèré, Diane; Malka, David

doi:10.1016/j.ejca.2017.01.010

Cited by 40 publications

(29 citation statements)

References 94 publications

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“…In thoracic surgery, multiple metastases can be treated using LASER resection, thus sparing lung parenchyma. Further strategies such as repeat surgery, radiofrequency or microwave ablation, stereotactic body radiotherapy, and selective internal radiotherapy support the management of metastatic recurrences . Last but not least, better imaging detects more precisely metastatic manifestations and allows better patient selection and more precise surgical guidance.…”

Section: Discussionmentioning

confidence: 99%

Prognosis in patients with synchronous colorectal cancer metastases after complete resection of the primary tumor and the metastases

Radulova-Mauersberger

Zschuppe

Kittner

et al. 2019

Journal of Surgical Oncology

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Background Synchronous metastases are considered a negative prognostic factor in patients with metastatic colorectal cancer (CRC). We investigated the outcomes of stage IV CRC patients undergoing complete gross resection (R0/1) of both the primary tumor and the metastases under the guidance of a multidisciplinary team (MDT). Methods All CRC patients with synchronous metastases were retrieved from a prospective database. Patients treated from 2006 to 2017 who underwent complete resection were analyzed. Various factors, including multiple metastatic sites and complex procedures, were investigated. Univariate and multivariate overall survival (OS) calculations were performed. Results Of 330 consecutive patients with synchronous metastases, 101 (30.6%) achieved an R0/1 status including 12 (11.9%) patients with multiple metastatic sites. Complex procedures were necessary in 45 (44.6%) patients. Five‐year OS was 53.0% for the R0/1 patient group. Multivariate analysis could not detect factors associated with prognosis. Conclusions With modern treatment, the prognosis of patients with synchronous CRC metastases can be improved. Decisions made by a MDT offered one‐third of patients a potentially curative approach to their stage IV disease. Despite the treatment of a high rate of patients with complex metastases necessitating complex procedures, we achieved a favorable 5‐year OS rate.

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Section: Discussionmentioning

confidence: 99%

Prognosis in patients with synchronous colorectal cancer metastases after complete resection of the primary tumor and the metastases

Radulova-Mauersberger

Zschuppe

Kittner

et al. 2019

Journal of Surgical Oncology

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“…Energy will be delivered locally through the probe to cause a predictable and controllable volume of tissue necrosis [35]. There are several ablative technologies available, including heat radiofrequency (RF) or microwaves (MW), cold (cryoablation) or electric pulses (irreversible electroporation [IRE]) [36] ( Table 1). The common factor among ablation therapies is that they are less invasive than surgery, have a shorter recovery time and have fewer major complications [37].…”

Section: Unfit Patients (Fig 1b)mentioning

confidence: 99%

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

et al. 2019

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Colorectal cancer (CRC) has the second-highest tumor incidence and is a leading cause of death by cancer. Nearly 20% of patients with CRC will have metastases at the time of diagnosis, and more than 50% of patients with CRC develop metastatic disease during the course of their disease. A group of experts from Medicine and Molecular Imaging met to discuss and provide a multidisciplinary consensus on the management of liver metastases in patients with CRC. The group defined the different scenarios in which the disease can present: fit or unfit patients with resectable liver metastases, patients with potential resectable liver metastases, and patients with unresectable liver metastases. Within each scenario, the different strategies and therapeutic approaches are discussed.

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“…Overall survival after RFA for colorectal lung metastases is 56% at 5 years, with a 92% local control rate for tumors <3 cm. RFA in liver tumors is slightly less successful; local recurrence is slightly higher than after surgical resection and comparative overall survival has not yet been studied in a prospective setting, though RFA for lung tumors provides similar overall survival and local control compared with published surgical data …”

Section: Regional Therapiesmentioning

confidence: 99%

“…has not yet been studied in a prospective setting, though RFA for lung tumors provides similar overall survival and local control compared with published surgical data. 174…”

Section: Lungmentioning

confidence: 99%

Historical perspective: Two decades of progress in treating metastatic colorectal cancer

Lee

Cardona

Russell

2019

Journal of Surgical Oncology

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Colorectal cancer is the third most commonly diagnosed cancer in the United States. While screening methods strive to improve rates of early stage detection, 25% of patients have metastatic disease at the time of diagnosis, with the most common sites being the liver, lung, and peritoneum. While once perceived as hopeless, the last two decades have seen substantial strides in the medical, surgical, and regional therapies to treat metastatic disease offering significant improvements in survival.

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The role of image-guided therapy in the management of colorectal cancer metastatic disease

Cited by 40 publications

References 94 publications

Prognosis in patients with synchronous colorectal cancer metastases after complete resection of the primary tumor and the metastases

Prognosis in patients with synchronous colorectal cancer metastases after complete resection of the primary tumor and the metastases

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

Historical perspective: Two decades of progress in treating metastatic colorectal cancer

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