“…Cytokines in IL-1 family consist of 7 agonists (such as IL-36α/β/γ), four cytokines having anti-inflammatory activities (such as IL-36Ra, IL-37, IL-38). [1][2][3][4][5][6] In recent years, the IL-36 subfamily, IL-37, IL-38 are recognized important in various immune response. Interleukin-36 subfamily includes IL-36α/β/γ, IL-36Ra, IL-36R, and IL-1RAcP.…”