2013
DOI: 10.36076/ppj.2013/16/e227
|View full text |Cite
|
Sign up to set email alerts
|

The Role of Hydromorphone and OPRM1 in Postoperative Pain Relief with Hydrocodone

Abstract: Background: Postoperative pain management remains a challenge for clinicians due to unpredictable patient responses to opioid therapy. Some of this variability may result from single nucleotide polymorphisms (SNPs) of the human opioid mu-1 receptor (OPRM1) that modify receptor binding or signal transduction. The OPRM1 variant with the highest frequency is the A118G SNP. However, previous studies have produced inconsistent results regarding the clinical effects of A118G on opioid response. We hypothesized that … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2017
2017
2022
2022

Publication Types

Select...
4
1

Relationship

0
5

Authors

Journals

citations
Cited by 10 publications
references
References 20 publications
0
0
0
Order By: Relevance