volume 8, issue 10, P2264-2289 2016
DOI: 10.18632/aging.101026
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Bernard W. Perridon, Henri G.D. Leuvenink, Jan-Luuk Hillebrands, Harry van Goor, Eelke M. Bos

Abstract: When humans grow older, they experience inevitable and progressive loss of physiological function, ultimately leading to death. Research on aging largely focuses on the identification of mechanisms involved in the aging process. Several proposed aging theories were recently combined as the ‘hallmarks of aging’. These hallmarks describe (patho-)physiological processes that together, when disrupted, determine the aging phenotype. Sustaining evidence shows a potential role for hydrogen sulfide (H2S) in the regula…

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