The role of genetic markers of thrombophilia in the development of thrombosis after coronary artery bypass graft surgery

Abstract

Coronary artery bypass grafting is one of the most common surgeries performed among all elective cardiac surgery operations. Starting from the first operations, thrombosis not only in the coronary arteries, but also in the venous system was the subject of attention. Over the past two decades it has become evident that the hypercoagulable state, or socalled thrombophilia is multifactorial, genetically determined disorder of the hemostatic system. This article provides an overview of studies on the role of genetic polymorphisms in the development of thrombosis after coronary artery bypass grafting.