The role of fiber durability/biopersistence of silica-based synthetic vitreous fibers and their influence on toxicology

Maxim, Laura; Hadley, John G.; Potter, Russell M.; Niebo, Ron

doi:10.1016/j.yrtph.2006.05.003

Cited by 69 publications

(53 citation statements)

References 91 publications

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“…One of the most important factors for defining the hazardousness of mineral fibers is their size or their tendency to split into smaller fibrils that are easily inhalable [3][4][5][6][7]. The biopersistence of fibers, defined as their ability to persist in the human body to chemical, physical, and other physiological clearance mechanisms, is another important factor for inducing toxicity and carcinogenicity [8][9][10]. Accordingly, it has been shown that an inhalable fiber might be carcinogenic if it is sufficiently durable to remain chemically and physically unaltered within the lung tissue [11].…”

Section: Introductionmentioning

confidence: 99%

Prismatic to Asbestiform Offretite from Northern Italy: Occurrence, Morphology and Crystal-Chemistry of a New Potentially Hazardous Zeolite

et al. 2018

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A multi-methodological approach, based upon field investigation, morphological characterization, chemical analysis and structure refinement was applied to different samples of fibrous offretite, a new potentially hazardous zeolite recently discovered in northern Italy. Their morphology ranges from stocky-prismatic to asbestiform. All the investigated fibers may be considered as "inhalable", and they are well within the range of the "more carcinogenic fibers" regarding diameter. As regards the length, the main mode observed in the asbestiform samples is 20-25 µm, and~93% of the measured fibers are >5 µm and may be significantly associated with carcinogenesis also in terms of lengths. The chemical-structural features of the investigated fibers are comparable: the extra-framework cations K + , Mg 2+ and Ca 2+ are present in all samples in similar proportions, and refined cell parameters are similar among the samples. Offretite occurs in 60% of the investigated sites, with an estimated amount up to 75 vol % of the associated minerals. The presence of this mineral could be of concern for risk to human health, especially if one considers the vast number of quarries and mining-related activities that are operating in the zeolite host rocks.

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Section: Introductionmentioning

confidence: 99%

Prismatic to Asbestiform Offretite from Northern Italy: Occurrence, Morphology and Crystal-Chemistry of a New Potentially Hazardous Zeolite

et al. 2018

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“…If the fibers are assumed to be cylinders with diameter that decreases as dissolution proceeds and the surface area of the fiber ends is neglected, the time for complete dissolution can be estimated from the following equation [7]:…”

Section: Estimation Of Dissolution Ratementioning

confidence: 99%

Dissolution behavior of calcium-magnesium-silicate glass fiber

Liu

Wang

Zhang

et al. 2011

J. Cent. South Univ. Technol.

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The dissolution behavior of CaO-MgO-SiO 2 glass fiber was investigated by scanning electron microscopy (SEM), Fourier-transform infrared spectrometer (FTIR) and inductively coupled plasma atomic emission spectroscopy (ICP-AES) using in-vitro tests. The results show that the soaked fiber is surrounded by an outer calcium-magnesium silicate hydrated layer, and there exists a balancing function between the formation and abscission of the hydrated layer during the dissolution process. The concentrations of leached ions increase constantly, and the mass loss of the fibers and pH changes of the solution are found to rise rapidly during the initial dissolution process, then their increasing rates are controlled by the balancing function of the hydrated layer at the subsequent dissolution stages. The dissolution rate constant and time for complete dissolution are estimated to be 274 ng/(cm 2 ·h) and 15.2 d, respectively, presenting preferable biosolubilities.

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“…En Europe, les FCR sont produites par fusion (> 2000 8C) d'une combinaison d'alumine (Al 2 O 3 ) et de silice (SiO 2 ) dans des proportions quasi équivalentes. D'autres oxydes inorganiques, comme le Zr 2 O 3 , le Cr 2 O 3 , le B 2 O 3 et le TiO 2 sont parfois ajoutés afin de modifier les propriétés physiques (durabilité ou température maximale d'utilisation) des produits [3,4]. Les FCR peuvent également être produites par fusion de mélange de kaolin, d'alumine et de silice.…”

Section: Productionunclassified

“…Ces fibres possèdent une faible conductivité thermique, une faible capacité calorifique (accumulation thermique), une excellente résistance aux chocs thermiques, un poids réduit, une bonne résistance à la corrosion et une facilité d'installation. En fonction de leur composition chimique, la température maximale d'utilisation peut atteindre les 1430 8C [4]. Les FCR sont donc utilisées comme matériau d'isolation à hautes températures.…”

Section: Propriétés Physicochimiques Des Fibres Céramiques Réfractairunclassified

“…Ainsi, la comparaison des mesures nécessitent des protocoles similaires et des analyses selon des modèles comparables. Pour différents auteurs, la conclusion est identique : les FCR sont plus biopersistantes que les laines de verre mais moins biopersistantes que l'amiante [9,12,13]. Les FCR ont les mêmes niveaux de biopersistance que les laines de roches traditionnelles.…”

Section: Biopersistanceunclassified

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Les fibres céramiques réfractaires : un danger pour l’Homme ? Revue de la littérature

Kiakouama

Faucon

2010

Archives des Maladies Professionnelles et de l'Environnement

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The role of fiber durability/biopersistence of silica-based synthetic vitreous fibers and their influence on toxicology

Cited by 69 publications

References 91 publications

Prismatic to Asbestiform Offretite from Northern Italy: Occurrence, Morphology and Crystal-Chemistry of a New Potentially Hazardous Zeolite

Prismatic to Asbestiform Offretite from Northern Italy: Occurrence, Morphology and Crystal-Chemistry of a New Potentially Hazardous Zeolite

Dissolution behavior of calcium-magnesium-silicate glass fiber

Les fibres céramiques réfractaires : un danger pour l’Homme ? Revue de la littérature

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