The Role of Extended Cervical Mediastinoscopy in Staging of Non-small Cell Lung Cancer of the Left Lung and a Comparison with Integrated Positron Emission Tomography and Computed Tomography: Does Integrated Positron Emission Tomography and Computed Tomography Reduce the Need for Invasive Procedures?

Metin, Muzaffer; Çıtak, Necati; Sayar, Adnan; Pekçolaklar, Atilla; Melek, Hüseyin; Kök, Abdülaziz; Gürses, Atilla

doi:10.1097/jto.0b013e318225914e

Cited by 34 publications

(22 citation statements)

References 23 publications

(27 reference statements)

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“…Therefore, PET-CT scans do not reduce the need for cervical mediastinoscopy in detecting nodal disease [15]. Our study supports the use of mediastinoscopy in the preoperative staging of lung cancer.…”

Section: Discussionsupporting

confidence: 69%

Mediastinoscopy in Assessing Mediastinal Lymphadenopathy and Lung Disease

Al-Githmi¹

2017

OJTS

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Background: Mediastinoscopy is the gold standard procedure for the pathological staging and diagnosis of mediastinal diseases. The aim of the study is to describe the significance of anterior cervical Mediastinoscopy in evaluating patients with mediastinal lymphadenopathy and lung parenchymal disease. Material and Methods: From January 2014 until June 2017 we conducted a retrospective study of 52 consecutive patients with mediastinal lymphadenopathy and lung parenchymal disease who underwent anterior cervical Mediastinoscopy. The main indications for cervical Mediastinoscopy were isolated mediastinal lymphadenopathy, undetermined lung mass with mediastinal lymphadenopathy, and the clinical staging of patients with lung cancer. Results: The study subjects consisted of 37 men and 15 women, aged 13 to 87 (mean age 50.8). Eight patients had mediastinoscopy for staging lung cancer, 27 patients had mediastinoscopy to diagnose isolated mediastinal lymphadenopathy, and 17 patients had mediastinoscopy for an undetermined lung parenchymal mass. Among the patients with isolated mediastinal lymphadenopathy, sarcoidosis was diagnosed in 6, tuberculosis in 9, reactive lymph nodes in 4, metastasis in 5 and lymphoma in 3. Lymph node metastasis (N2, N3) was found in 5 patients with lung cancer. There was no surgical-related mortality or morbidity. Conclusions: Mediastinoscopy is a safe and reliable procedure in diagnosing mediastinal diseases and is still the first choice among the investigative modalities in the clinical staging of bronchogenic carcinoma.

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Section: Discussionsupporting

confidence: 69%

Mediastinoscopy in Assessing Mediastinal Lymphadenopathy and Lung Disease

Al-Githmi¹

2017

OJTS

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“…Perigaud et al [32] reported the specificity is high: patients with negative integrated 18 F-FDG PET/CT can be operated upon directly without invasive mediastinal staging. While one study of Metin et al [33] showed that PET/CT does not reduce the need for invasive procedures in detecting lymph node metastasis in aortopulmonary window. By integrating functional and anatomic data, PET/CT is the best noninvasive method for the detection of nodal metastasis, but mediastinoscopy remains the gold standard [25, 33].…”

Section: Stagingmentioning

confidence: 99%

PET/CT in the Staging of the Non-Small-Cell Lung Cancer

Chao

Zhang

2012

Journal of Biomedicine and Biotechnology

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Lung cancer is a common disease and the leading cause of cancer-related death in many countries. Precise staging of patients with non-small-cell lung cancer plays an important role in determining treatment strategy and prognosis. Positron emission tomography/computed tomography (PET/CT), combining anatomic information of CT and metabolic information of PET, is emerging as a potential diagnosis and staging test in patients with non-small-cell lung cancer (NSCLC). The purpose of this paper is to discuss the value of integrated PET/CT in the staging of the non-small-cell lung cancer and its health economics.

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“…Mediastinal lenf nodları için geç görüntüleme yapılması durumunda daha iyi duyarlılık değerlerinin elde edilebileceği bildirilmiştir (14). FDG PET-BT için literatürde bildirilen bu olumlu sonuçlara rağmen, mediastinoskopi yerine bu noninvaziv yöntemin kullanılamayacağı ayrıca vurgulanmıştır (15,16). Mikrometastazlar nedeniyle literatürde %8'e varan yanlış negatif sonuçlar bildirilmiş olup, granü-lomatöz hastalıklar nedeni ile yanlış pozitif sonuçlar alınabileceği de yine akılda tutulmalıdır (17).…”

Section: Akci̇ğer Kanserleri̇unclassified

Pet Applications For Staging And Restaging In Thoracic Malignancies

Öneş¹,

Erdıl²

2015

Toraks Cer Bult

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In the last 10 years, Fluorine-18 fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) scan has been widely adopted in thoracic oncology, showing high accuracy in staging and restaging. The aim of this review was to focus on the results of PET scan use in the evaluation of thoracic malignancies. The literature search was performed on January 2015 in PubMed and Google Academic. The search was restricted to publications in English, using in the same string the word "PET" with different thoracic tumors. From 3000 papers initially selected, the irrelavant articles eliminated and then approximately 100 manuscripts were fully analyzed. In conclusion, positron emmision tomography/ computed tomography (PET-CT) has established itself as an important step in the evaluation of patients with thoracic malignancies. Further evaluation and come into use of newer PET tracers and simultaneous Magnetic Resonance Imaging (MRI) with PET (PET/MR) imaging will offer additional options in thoracic oncology in future.

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The Role of Extended Cervical Mediastinoscopy in Staging of Non-small Cell Lung Cancer of the Left Lung and a Comparison with Integrated Positron Emission Tomography and Computed Tomography: Does Integrated Positron Emission Tomography and Computed Tomography Reduce the Need for Invasive Procedures?

Abstract: ECM, which is an effective technique used in the determination of APW lymph node metastasis, was enough to rule out nodal disease with negative predictive value. PET/CT does not reduce the need for invasive procedures in detecting APW lymph node metastasis.

Cited by 34 publications

References 23 publications

Mediastinoscopy in Assessing Mediastinal Lymphadenopathy and Lung Disease

Mediastinoscopy in Assessing Mediastinal Lymphadenopathy and Lung Disease

PET/CT in the Staging of the Non-Small-Cell Lung Cancer

Pet Applications For Staging And Restaging In Thoracic Malignancies

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