The Role of Ethics in Public Health Clinical Research

Fokunang, C. N.; Tembe-Fokunang, EA; Awah, Paschal Kum; DjuidjeNgounoue, M.; C., P.; Ateudjieu, Jérôme; Langsi, Raymond; Kaptué, Lazare; Abena, Obama

doi:10.5772/52478

Cited by 2 publications

(4 citation statements)

References 45 publications

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“…In most countries, manufacturers are required to submit reports they receive from healthcare providers to the national authority. Others have intensive, focused program concentrating on new drugs, even controversial drugs, along with the prescribing habits of groups of doctors involving pharmacists in reporting to generate potentially useful information [4].…”

Section: Other Reporting Methodsmentioning

confidence: 99%

“…Pharmacovigilance (PHV), a French term referring to identifying side effects of drugs, their treatment, documentation, reportage and regulatory decisions based on them, is a wellestablished science in the developed world [4]. Pharmacovigilance is the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects or any other drug related problems, particularly long term and short-term side effects of medicines [5].…”

Section: Pharmacovigilancementioning

confidence: 99%

“…Myriads of herbal products are self-prescribed for minor as well as severe chronic diseases [8]. Self-medication is associated with serious health concerns like delay in effective treatment, interference with vital treatment, overloading patient with multiple medication, lack of communication with practitioner, weak or missing information and side effects or ADRs [4,20].…”

Section: Self-medication Issuesmentioning

confidence: 99%

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Pharmacovigilance of Natural Herbal Medicines Research for Efficacy, Safety and Quality Assurance of Phytomedicine Products

Fokunang

Fonmboh

Mballa

et al. 2020

JOCAMR

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Improved traditional medicine/phytomedicine formulations have gained a global acceptability and popularity as therapeutic agents for many diseases in Sub-Saharan Africa. Herbal products are generally considered as safe, environmentally friendly and increasingly consumed by the community without prescription. There is a lack of systematic data on traditional medicine-associated adverse effects due to complex issues such as products with multiple ingredients, poor standardization, lack of clinical trials, variation in manufacturing processes, contamination, adulteration and misidentification of herbs. The aim of pharmacovigilance is to detect, assess, understand, and prevent the adverse effects or any other possible drug-related problems, related to herbal, traditional and complementary medicines. Pharmacovigilance for herbal medicines is in its infancy, and monitoring the safety of natural products presents unique challenges, and as such, preparations are available from a wide range of sources where limited qualified healthcare professionals are available. The ethico-legal issues and regulatory approval mechanism of herbal medicine vary from country to country. This paper also elucidates the level of challenges associated with herbal pharmacovigilance geared towards improving safety monitoring for herbal medicines in the future.

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Section: Other Reporting Methodsmentioning

confidence: 99%

Section: Pharmacovigilancementioning

confidence: 99%

Section: Self-medication Issuesmentioning

confidence: 99%

See 1 more Smart Citation

Pharmacovigilance of Natural Herbal Medicines Research for Efficacy, Safety and Quality Assurance of Phytomedicine Products

Fokunang

Fonmboh

Mballa

et al. 2020

JOCAMR

View full text Add to dashboard Cite

show abstract

“…The consequent discrimination against the susceptible was against all norms of public health ethics which seek to secure adequate health for all and to minimise inequalities. Stigmatisation, leading to delay in treatment-seeking and aggravating disease transmission, yields poor health outcomes (2). Furthermore, health-related stigma exacerbates pre-existing divisions in communities such as race, gender, religion, and class (3,4).…”

mentioning

confidence: 99%