2015
DOI: 10.17554/j.issn.2409-3548.2015.01.14
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The Role of Erythropoietin and its Receptor in the Immune, Central Nervous and Cardiovascular Systems

Abstract: Primary role of erythropoietin (EPO) is to protect red blood cell progenitors from apoptosis and to stimulate their growth and differentiation by binding to its receptor (EPOR). However, the expression of EPOR has been identified on other human cells, such as granulocytes, monocytes, lymphocytes, endothelial cells and neurons. Its presence on these cells suggests that beyond erythropoietic function EPO might have some other properties. Various studies show that recombinant human erythropoietin (rhEPO) used in … Show more

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