The role of endoscopy in the management of patients with peptic ulcer disease

Banerjee, Subhas; Cash, Brooks D.; Dominitz, Jason A.; Baron, Todd H.; Anderson, Michelle A.; Ben–Menachem, Tamir; Fisher, Laurel; Fukami, Norio; Harrison, M. Edwyn; Ikenberry, Steven O.; Khan, Khalid; Krinsky, Mary Lee; Maple, John T.; Fanelli, Robert D.; Strohmeyer, Laura

doi:10.1016/j.gie.2009.11.026

Cited by 118 publications

(61 citation statements)

References 54 publications

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“…A second endoscopic procedure is generally not recommended within 24 h after the initial one, however it is appropriate in cases in which clinical signs indicate recurrent bleeding or if hemostasis during the initial procedure is questionable [6]. A meta-analysis found that routinely repeating endoscopy reduces the rate of recurrent bleeding but not the need for surgery or the risk of death.…”

Section: Hemorrhagementioning

confidence: 99%

Complications of Peptic Ulcer Disease

Milosavljević

Kostić-Milosavljević

Jovanović

et al. 2011

Dig Dis

103

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There are four major complications of peptic ulcer disease (PUD): bleeding, perforation, penetration, and obstruction. Complications can occur in patients with peptic ulcer of any etiology. Despite improvements in the medical management and the lower overall incidence of PUD, there are conflicting data about the incidence of potentially life-threatening ulcer complications. There are important time trends embedded within this stable overall rate of complications: the dramatic decline in the prevalence of Helicobacter pylori (comparing the cohort born from 1900 to 1920 to cohorts born after 1940); an increased use of nonsteroidal anti-inflammatory drugs, and an increased rate of ulcer complications related to such drug use, especially in the elderly. As a result of these trends, ulcer complications are on the rise in older patients but on the decline in younger individuals. Hemorrhage is the most frequent PUD complication and its incidence is increasing in comparison to perforation and stenosis. Therapeutic endoscopy is considered the treatment of choice for bleeding ulcers, reducing the need for emergent surgical procedures to 10–20% of the cases. In recent years, besides the success of angiographic embolization, the containment of massive hemorrhage must also be taken into account. Transcatheter arterial embolization is also an effective and safe treatment in patients with duodenal ulcers re-bleeding after therapeutic endoscopy or surgery.

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Section: Hemorrhagementioning

confidence: 99%

Complications of Peptic Ulcer Disease

Milosavljević

Kostić-Milosavljević

Jovanović

et al. 2011

Dig Dis

103

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show abstract

“…10 Unfortunately, gastric ulcers that are endoscopically and histologically benign may be gastric cancer eventually. 11 To exclude underlying malignancies for gastric ulcers, surveillance endoscopy is a common practice to confirm ulcer healing in patients with gastric ulcer diseases. 12 However, routine surveillance endoscopy in gastric ulcer patients not only increases procedure-related risks and consumes medical resources but also increases patient anxiety.…”

mentioning

confidence: 99%

A Tool to Predict Risk for Gastric Cancer in Patients With Peptic Ulcer Disease on the Basis of a Nationwide Cohort

Lee

Wang

Chen

et al. 2015

Clinical Gastroenterology and Hepatology

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“…Gastric ulcers >5 cm in diameter in the cardia region are particularly associated with a very high probability of malignancy. Endoscopic surveillance should be considered if other demographic risk factors are present, such as old age, family history of gastric cancer, and H. pylori infections (8,36,37). …”

Section: Discussionmentioning

confidence: 99%

“…In addition, approximately 5% of endoscopic benign-appearing gastric ulcers are malignant (4,5). Although the current British guidelines recommend that all gastric ulcers should be followed with repeated endoscopy and biopsy until they heal (6,7), the American Society for Gastrointestinal Endoscopy does not recommend routine endoscopic surveillance for patients with gastric ulcers (8). Surveillance endoscopy is recommended in Korea at 4-8 weeks after the treatment of a benign gastric ulcer (9).…”

Section: Introductionmentioning

confidence: 99%