The role of dysfunctional breathing in asthma control

Veidal, Sandra; Sverrild, Asger; Backer, Vibeke; Porsbjerg, Celeste

doi:10.1183/13993003.congress-2015.oa4480

Cited by 2 publications

(2 citation statements)

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“…DB affects a substantial proportion of patients with difficult asthma . One study of general asthma patients found worse asthma control scores in those with DB . DB can lead to breathlessness disproportionate to airflow obstruction and an overestimation of the severity of asthma symptoms.…”

Section: Discussionmentioning

confidence: 99%

Comorbidities in difficult asthma are independent risk factors for frequent exacerbations, poor control and diminished quality of life

et al. 2016

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Background and objective:Little is known about how comorbidities affect difficult asthma patients across different domains of asthma outcomes. We hypothesized that comorbidities in difficult asthma significantly influence asthma outcomes. Methods: We analysed 90 consecutive patients who underwent systematic assessment at our hospital's difficult asthma clinic. Eight comorbidities were assessed in all patients. They were allergic rhinitis, chronic rhinosinusitis (CRS), gastroesophageal reflux disease, obesity, obstructive sleep apnoea, anxiety or depression, dysfunctional breathing (DB) and vocal cord dysfunction (VCD). Asthma outcomes examined were exacerbation frequency (≥3/year vs <3/year), asthma control using the Asthma Control Test (ACT) and quality of life using the Asthma Quality of Life Questionnaire (AQLQ). Multivariate logistic regression was performed for dichotomous outcomes and linear regression for continuous outcomes. Analyses were adjusted for lung function and absolute blood eosinophils. Conclusion: Comorbidities independently impact a broad spectrum of outcomes in difficult asthma. Systematic evaluation of these conditions is essential in difficult asthma.

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Section: Discussionmentioning

confidence: 99%

Comorbidities in difficult asthma are independent risk factors for frequent exacerbations, poor control and diminished quality of life

et al. 2016

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“…Based on the Nijmegen Questionnaire and using a score ≥23, the prevalence of DB in asthma was 29% in a primary care setting and 24.4% in a secondary care setting . Using the same definition, the prevalence of DB in difficult asthma was higher, at 30%‐64% …”

Section: How Common Are Comorbidities In Difficult Asthma?mentioning

confidence: 99%

Comorbid “treatable traits” in difficult asthma: Current evidence and clinical evaluation

Tay

Hew

2017

Allergy

126

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The care of patients with difficult-to-control asthma ("difficult asthma") is challenging and costly. Despite high-intensity asthma treatment, these patients experience poor asthma control and face the greatest risk of asthma morbidity and mortality.Poor asthma control is often driven by severe asthma biology, which has appropriately been the focus of intense research and phenotype-driven therapies. However, it is increasingly apparent that extra-pulmonary comorbidities also contribute substantially to poor asthma control and a heightened disease burden. These comorbidities have been proposed as "treatable traits" in chronic airways disease, adding impetus to their evaluation and management in difficult asthma. In this review, eight major asthma-related comorbidities are discussed: rhinitis, chronic rhinosinusitis, gastroesophageal reflux, obstructive sleep apnoea, vocal cord dysfunction, obesity, dysfunctional breathing and anxiety/depression. We describe the prevalence, impact and treatment effects of these comorbidities in the difficult asthma population, emphasizing gaps in the current literature. We examine the associations between individual comorbidities and highlight the potential for comorbidity clusters to exert combined effects on asthma outcomes. We conclude by outlining a pragmatic clinical approach to assess comorbidities in difficult asthma.

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The role of dysfunctional breathing in asthma control

Cited by 2 publications

References 0 publications

Comorbidities in difficult asthma are independent risk factors for frequent exacerbations, poor control and diminished quality of life

Comorbidities in difficult asthma are independent risk factors for frequent exacerbations, poor control and diminished quality of life

Comorbid “treatable traits” in difficult asthma: Current evidence and clinical evaluation

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