The Role Of Diffusion-Weighted Mr Imaging And Adc Values In The Diagnosis Of Gastric Tumors

Prospective comparison of 3T MRI with diffusion‐weighted imaging and MDCT for the preoperative TNM staging of gastric cancer

“…Using MPR and 3D reconstructed images, the diagnostic accuracy of T staging using MDCT has been reported to have increased (12,27,34), and several recent studies have shown an 83% to 91% overall accuracy of T staging by MDCT with MPR images by using the AJCC 7th guidelines as pathologic references 11,35). In addition, several previous studies on gastric MRI have demonstrated the value of DWI in gastric cancers for detecting tumors and obtaining a differential diagnosis of gastric cancers from lymphoma or other benign conditions (36,37). In our study, adding DWI to conventional T 1 -and T 2 -weighted images and dynamic imaging did not significantly increase the diagnostic performance compared with conventional MRI.…”

Whole body MRI: Improved lesion detection and characterization with diffusion weighted techniques

“…In this study, initial pretreatment ADC values for poor responders was 1.24 versus 1.06 [Â 10 À3 ] s/mm 2 for good responders, with the good responders demonstrating response to therapy by 1 week, characterized by an increase in ADC value to a mean of 1.60 [Â 10 À3 ] s/mm 2 (111). DWI alone has been shown to aid in stomach mass lesion detection, with the possibility to discriminate between adenocarcinoma and lymphoma (112).…”

Assessment of histological differentiation in gastric cancers using whole-volume histogram analysis of apparent diffusion coefficient maps

“…MRI with DWI can increase the sensitivity and accuracy of TNM staging for gastric cancer, especially T staging . In quantitative terms, the apparent diffusion coefficient (ADC) values could help differentiate between gastric cancers and normal gastric mucosa as well as between gastric adenocarcinoma and lymphoma . Previous studies have also shown that the ADC values may be helpful as a noninvasive tool for evaluating the histological features, HER‐2 status, and TNM staging of gastric cancer .…”