The Role of Conventional MR Imaging Sequences in the Evaluation of Neurocysticercosis: Impact on Characterization of the Scolex and Lesion Burden

Lucato, Leandro Tavares; Guedes, M. S.; Sato, João Ricardo; Bacheschi, Luiz Alberto; Machado, L. R.; Leite, Cláudia C.

doi:10.3174/ajnr.a0623

Cited by 76 publications

(62 citation statements)

References 23 publications

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“…In T1-weighted and FLAIR images, when the intraventricular cyst can be identified, the cyst wall and scolex present intermediate to high intensity 7 . Many previous papers have studied the best MRI protocol for the diagnosis of NCC [15][16][17] , but these have focused mainly on parenchymal involvement. Few papers have focused on the application of MR sequences in the diagnosis of intraventricular NCC, despite the fact that this is one of the most severe forms of NCC 7,11,18,19 .…”

Section: Discussionmentioning

confidence: 99%

The role of 3D volumetric MR sequences in diagnosing intraventricular neurocysticercosis: preliminar results

Filho

Machado

Lucato

et al. 2011

Arq. Neuro-Psiquiatr.

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Objective: The purpose of this paper was to investigate the role of two three-dimensional magnetic resonance (MRI) sequences: enhanced spoiled gradient recalled echo (SPGR), and fast imaging employing steady-state acquisition (FIESTA) in the evaluation of intraventricular neurocysticercosis cysts and scolices. Method: Seven neurocysticercosis patients suspected of presenting intraventricular lesions were evaluated by magnetic resonance imaging using enhanced SPGR, and FIESTA. Results: Enhanced SPGR detected eight cystic lesions, with scolices in four. Contrast enhancement was observed in three cysts. FIESTA also detected eight cystic lesions with the presence of scolices in seven of those cystic lesions. Four patients presented parenchymal involvement, while the remaining three presented the racemose form. Conclusion: FIESTA and SPGR are sequences that can detect intraventricular cysts of neurocysticercosis, and FIESTA also is good for the detection of the scolex. Considering this information we suggest that FIESTA and SPGR should be included in the MRI protocol for the investigation of intraventricular neurocysticercosis. Key words: intraventricular neurocysticercosis, magnetic resonance imaging, FIESTA, SPGR.Papel das sequencias volumétricas 3D de RM no diagnóstico da neurocisticercose intraventricular: resultados preliminares RESUMO Objetivo: O objetivo deste trabalho foi investigar o papel de duas sequências de ressonância magnética (RM) volumétricas tridimensionais: spoiled gradient recalled echo (SPGR) pós-contraste e fast imaging employing steady-state acquisition (FIESTA) na avaliação de cistos e escólex na neurocisticercose intraventricular. Método: Sete pacientes suspeitos de neurocisticercose intraventricular foram avaliados pela ressonância magnética com SPGR pós-contraste e FIESTA. Resultados: SPGR pós-contraste evidenciou oito lesões císticas com presença de escólex em quatro. Realce foi observado em três destes cistos. FIESTA também detectou oito lesões císticas, com presença de escólex em sete destas lesões. Envolvimento do parênquima cerebral foi observado em quatro pacientes e forma racemosa em três. Conclusão: FIESTA e SPGR são sequências que permitem a detecção de cistos intraventriculares de neurocisticercose e FIESTA é uma boa sequência para a detecção de escólex. Considerando estes achados nós sugerimos que estas sequências (FIESTA e SPGR) devam ser incluídas no protocolo de RM na investigação de neurocisticercose intraventricular. Palavras-chave: neurocisticercose intraventricular, ressonância magnética, FIESTA, SPGR.

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Section: Discussionmentioning

confidence: 99%

The role of 3D volumetric MR sequences in diagnosing intraventricular neurocysticercosis: preliminar results

Filho

Machado

Lucato

et al. 2011

Arq. Neuro-Psiquiatr.

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“…In the vesicular phase the larva lives inside a translucent liquidfilled cystic structure surrounded by a thin membrane. The CT scan depicts circumscribed, rounded, hypodense areas, varying in size and number, without enhancement by contrast media [34]. With the MRI, the vesicular larva appears with a CSF-like intensity signal on all sequences.…”

Section: Immunological and Imaging Diagnosismentioning

confidence: 99%

“…Extraparenchymal NCC is more difficult to detect by imaging because the attenuation and signal intensity of the cyst's content is similar to that of CSF, the cystic wall is usually very thin and the cysts lack frequently of a scolex and generally not enhanced after contrast administration. In these cases, new MRI techniques such as fluid attenuated inversion recovery (FLAIR) and fast imaging employing steady-state acquisition (FIESTA) sequences, that seems to permit a better diagnosis (34)(35)(36) (Figure 2) . A common neuroimaging finding is hydrocephalus related to inflammatory occlusion of Luschka and Magendie foramina and C A B D basal fibrous arachnoiditis [36].…”

Section: Immunological and Imaging Diagnosismentioning

confidence: 99%

Clinical Diagnoses of Neurocysticercosis

Carpio¹

2013

Novel Aspects on Cysticercosis and Neurocysticercosis

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“…Inactive lesions are depicted as rounded, hypodense, without enhancement and with areas of calcification 28 . MRI is the best test for definition of the cyst stage in their evolution in the brain on T1, T2, FLAIR sequences, including the inflammatory aspects when using enhanced images with gadolinium infusion ( Figures 3A, B and C) 29 although not as accurate in detection of calcifications. Diffusion weighted images were demonstrated as better defining the scolex and increasing the confidence for the NCC diagnosis by MRI 30 .…”

Section: The Quest For the Neuroimagingmentioning

confidence: 99%

Neurocysticercosis, familial cerebral cavernomas and intracranial calcifications: differential diagnosis for adequate management

Gasparetto

Alves-Leon

Domingues

et al. 2016

Arq. Neuro-Psiquiatr.

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Neurocysticercosis (NCC) is an endemic disease and important public health problem in some areas of the World and epilepsy is the most common neurological manifestation. Multiple intracranial lesions, commonly calcified, are seen on cranial computed tomography (CT) in the chronic phase of the disease and considered one of the diagnostic criteria of the diagnosis. Magnetic resonance imaging (MRI) is the test that better depicts the different stages of the intracranial cysts but does not show clearly calcified lesions. Cerebral cavernous malformations (CCM), also known as cerebral cavernomas, are frequent vascular malformations of the brain, better demonstrated by MRI and have also epilepsy as the main form of clinical presentation. When occurring in the familial form, cerebral cavernomas typically present with multiple lesions throughout the brain and, very often, with foci of calcifications in the lesions when submitted to the CT imaging. In the countries, and geographic areas, where NCC is established as an endemic health problem and neuroimaging screening is done by CT scan, it will be important to consider the differential diagnosis between the two diseases due to the differences in adequate management.

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The Role of Conventional MR Imaging Sequences in the Evaluation of Neurocysticercosis: Impact on Characterization of the Scolex and Lesion Burden

Cited by 76 publications

References 23 publications

The role of 3D volumetric MR sequences in diagnosing intraventricular neurocysticercosis: preliminar results

The role of 3D volumetric MR sequences in diagnosing intraventricular neurocysticercosis: preliminar results

Clinical Diagnoses of Neurocysticercosis

Neurocysticercosis, familial cerebral cavernomas and intracranial calcifications: differential diagnosis for adequate management

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