The Role of Computed Tomography in the Management of the Neck After Chemoradiotherapy in Patients With Head-and-Neck Cancer

Fractional Change in Apparent Diffusion Coefficient as an Imaging Biomarker for Predicting Treatment Response in Head and Neck Cancer Treated with Chemoradiotherapy

“…With regard to the regional recurrence after chemoradiotherapy, it has been reported that lymph node residual size and the regression rate of nodal maximal diameter or nodal volume after treatment might be useful for the prediction of regional recurrence. 22,23 In this study, we evaluated the usefulness of the tumor regression ratio at 3 weeks after the start of chemoradiotherapy for prediction of LRC. As a result, ⌬TV node revealed a significant difference between LRC and LRF and showed significant association with LRC in univariate analysis.…”

Predictive factors of survival and treatment tolerance in older patients treated with chemotherapy and radiotherapy for locally advanced head and neck cancer

“…If residual disease was observed on the CT scan (defined as reduction in lymph node diameter of less than 80% [19]) or at the clinical examination, a complementary neck dissection was offered to patients.…”

Influence of dosimetric and clinical criteria on the requirement of artificial nutrition during radiotherapy of head and neck cancer patients

“…As in all other investigations, gender was irrelevant for impaired deglutition [20][21][22][23][24]56,57]. The patients age is discussed controversially.…”

“…Consequently, the identification of factors predicting the requirement of artificial nutrition would be helpful to avoid unnecessary risks for the patients. In a number of previous studies, clinical characteristics, such as male gender [20][21][22][23][24], advanced age [17,20,22,23,[25][26][27], poor ECOG Score [4,13,28,29], low BMI [17,22], nicotine abuse [30], high TNM stage [3,4,17,20,22,25], tumor localization in the nasopharynx [20,31], and tracheotomy [32] as well as treatment characteristics like concurrent chemotherapy [3,21,[33][34][35], accelerated fractioning of radiation therapy [36] have been identified to be associated with an higher risk of swallowing problems. More recently, dose volume parameters derived from several normal tissue structures in the head and neck region were evaluated for their potential to predict acute and late radiation induced swallowing problems.…”