The role of common genetic markers in susceptibility to type 1 diabetes and autoimmune thyroid diseases

Репина, Е. А.

doi:10.14341/2072-0351-5630

Cited by 2 publications

(2 citation statements)

References 94 publications

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“…Часто АИГ встречается в рамках аутоиммунного полигландулярного синдрома (АПС) 2 и 3 типа, сопровождая СД1, АИЗ щитовидной железы, надпочечниковую недостаточность и другие аутоиммунные поражения неэндокринных органов. Предрасположенность к развитию АИГ в рамках АПС определяется в первую очередь наличием гаплотипа DQA1*0501 [12][13][14].…”

Section: этиология аутоиммунного гастритаunclassified

Autoimmune gastritis: comorbid pathology in type 1 diabetes

Derevyanko¹,

Сергеевна²,

Ибрагимова

et al. 2018

Diabetes mellitus

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In recent years noted an increased number of patients with autoimmune diseases (AID), and the special attention deserves combination of several autoimmune pathologies collected in one patient, because such patients requires special tactics of management. Autoimmune diseases of the gastrointestinal tract are less researched and, nevertheless, prognostically unfavorable. Autoimmune gastritis (AIG) has a special place in other stomach diseases, which develops in the aggregate with type 1 diabetes. AIG is a chronic inflammation of the mucous membrane of the body of the stomach, leading to the appearance of atrophy and hypoxecretion. AIG is found in 510% of individuals in general population, with a higher incidence of AIG in patients with diabetes and other established autoimmune pathology. AIG is asymptomatic at the early stage of the disease and clinical manifestations appear after the atrophic changes in the mucous membrane of the stomach develop. Since autoimmune gastritis does not have pathognomonic signs, it can manifest itself in hematological and oncological complications at later stages. This is why screening, early diagnosis, prevention and treatment are very important. Early diagnosis and prevention of AIG and its complications play the main role. This article provides an overview of the worldwide data dedicated to this issue.

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Section: этиология аутоиммунного гастритаunclassified

Autoimmune gastritis: comorbid pathology in type 1 diabetes

Derevyanko¹,

Сергеевна²,

Ибрагимова

et al. 2018

Diabetes mellitus

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“…Из всех ва-риантов сочетаний АИЗ наиболее четко это прослежива-ется для СД1 и аутоиммунных заболеваний щитовидной железы (АИЗ ЩЖ) [6][7][8][9][10]. Распространенность АИЗ ЩЖ у родственников больных СД1 достигает 48% по срав-нению с общей популяцией -лишь 3-10% [6,[11][12][13].…”

Section: /2013unclassified

Comparative analysis of HLA II allele and genotype frequency distribution in patients with type 1 diabetes mellitus and autoimmune thyroiditis

et al. 2013

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Сравнительный анализ распределения частот аллелей и генотипов HLA II класса у пациентов с сахарным диабетом 1 типа в отсутствие и в сочетании с аутоиммунным тиреоидитом Репина Е.А., Атаманова Т.М., Зверева Я.С., Тишина Ю.В., Прокофьев С.А. ФГБУ Эндокринологический научный центр

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The role of common genetic markers in susceptibility to type 1 diabetes and autoimmune thyroid diseases

Cited by 2 publications

References 94 publications

Autoimmune gastritis: comorbid pathology in type 1 diabetes

Autoimmune gastritis: comorbid pathology in type 1 diabetes

Comparative analysis of HLA II allele and genotype frequency distribution in patients with type 1 diabetes mellitus and autoimmune thyroiditis

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