The role of co-administration of magnesium sulfate with QTc-prolonging medications in the emergency department

Hoffer, Megan; Mazer‐Amirshahi, Maryann; Hodgson, Ryan; Pourmand, Ali

doi:10.1016/j.ajem.2021.03.075

The American Journal of Emergency Medicine

2022

DOI: 10.1016/j.ajem.2021.03.075

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The role of co-administration of magnesium sulfate with QTc-prolonging medications in the emergency department

Megan Hoffer

Maryann Mazer‐Amirshahi

Ryan Hodgson

et al.

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2023

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Cited by 1 publication

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Adjunctive Therapeutics in the Management of Cardiopulmonary Resuscitation: A Narrative Literature Review

Hoffer,

Pena,

Tran

et al. 2023

JCM

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Nearly 565,000 patients will suffer from prehospital and inpatient cardiac arrest in the United States per annum. Cardiopulmonary resuscitation and all associated interventions used to achieve it remain an essential focus of emergency medicine. Current ACLS guidelines give clear instructions regarding mainstay medications such as epinephrine and antiarrhythmics; however, the literature remains somewhat controversial regarding the application of adjunctive therapeutics such as calcium, magnesium, sodium bicarbonate, and corticosteroids. The available data acquired in this field over the past three decades offer mixed pictures for each of these medications on the effects of core metrics of cardiopulmonary resuscitation (e.g., rate of return of spontaneous circulation, survival-to-hospitalization and discharge, 24 h and 30 d mortality, neurological outcome), as well as case-specific applications for each of these interventions (e.g., polymorphic ventricular tachycardia, electrolyte derangements, acidosis, post-arrest shock). This narrative literature review provides a comprehensive summary of current guidelines and published data available for these four agents and their use in clinical practice.

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Adjunctive Therapeutics in the Management of Cardiopulmonary Resuscitation: A Narrative Literature Review

Hoffer,

Pena,

Tran

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

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The role of co-administration of magnesium sulfate with QTc-prolonging medications in the emergency department

Cited by 1 publication

References 22 publications

Adjunctive Therapeutics in the Management of Cardiopulmonary Resuscitation: A Narrative Literature Review

Adjunctive Therapeutics in the Management of Cardiopulmonary Resuscitation: A Narrative Literature Review

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